Evidence map›Paper›PMID 36387057›Full record

ArticleOncoimmunology2022

Spermidine rejuvenates T lymphocytes and restores anticancer immunosurveillance in aged mice.

Francesca Castoldi, Guido Kroemer, Federico Pietrocola

Open access · goldAbstract readComment
In one paragraph

Article in Oncoimmunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Tumorous IRE1α facilitates CD8Cell communication and signaling : CCS · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Francesca CastoldiDepartment of Biosciences and Nutrition, Karolinska Institute, 14152, Huddinge, Sweden.
Guido KroemerCentre de Recherche des Cordeliers, Equipe labellisé par la Ligue contre le cancer, Université de Paris Cité, Sorbonne Université, Inserm U1138, Institut Universitaire de France, Paris, France.
Federico PietrocolaDepartment of Biosciences and Nutrition, Karolinska Institute, 14152, Huddinge, Sweden.ORCID 0000-0002-2930-234X
Karolinska Institutet · SEInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Writing in

Indexed as

ImmunotherapySpermidineAnimalsCell Line, TumorLymphocyte CountMiceMonitoring, ImmunologicSpermidineAgingautophagyimmune checkpointsmitochondria

Identifiers

PMID36387057
PMCPMC9665084
OpenAlexW4308999690

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.