Evidence map›Paper›PMID 36386923›Full record

ArticleFrontiers in nutrition2022

Extra virgin olive oil extract rich in secoiridoids induces an anti-inflammatory profile in peripheral blood mononuclear cells from obese children.

Stefania De Santis, Pasquale Crupi, Laura Piacente, Anna Mestice, Nicola Antonio Colabufo, Loredana Amodio, Paola Pontrelli, Loreto Gesualdo, Antonio Moschetta, Maria Lisa Clodoveo and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Stefania De SantisDepartment of Pharmacy-Pharmaceutical Science, University of Bari Aldo Moro, Bari, Italy.
Pasquale CrupiDepartment of Interdisciplinary Medicine, University of Bari Aldo Moro, Bari, Italy.
Laura PiacentePediatric Unit, Department of Biomedical Sciences and Human Oncology, University of Bari Aldo Moro, Bari, Italy.
Anna MesticeHematology Unit, Department of Emergency and Organ Transplantation, University of Bari Aldo Moro, Bari, Italy.
Nicola Antonio ColabufoDepartment of Pharmacy-Pharmaceutical Science, University of Bari Aldo Moro, Bari, Italy.
Loredana AmodioBiofordrug, Laboratory for Clinical and Chemical Analyses, Bari, Italy.
Paola PontrelliNephrology Unit, Department of Emergency and Organ Transplantation, University of Bari Aldo Moro, Bari, Italy.
Loreto GesualdoNephrology Unit, Department of Emergency and Organ Transplantation, University of Bari Aldo Moro, Bari, Italy.
Antonio MoschettaDepartment of Interdisciplinary Medicine, University of Bari Aldo Moro, Bari, Italy.
Maria Lisa ClodoveoDepartment of Interdisciplinary Medicine, University of Bari Aldo Moro, Bari, Italy.
Maria Felicia FaienzaPediatric Unit, Department of Biomedical Sciences and Human Oncology, University of Bari Aldo Moro, Bari, Italy.
Filomena CorboDepartment of Pharmacy-Pharmaceutical Science, University of Bari Aldo Moro, Bari, Italy.
University of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity represents an important public health challenge of the twenty first century reaching epidemic proportions worldwide; this is especially true for the pediatric population. In this context, bioactive compounds from foods are crucial to counteract chronic inflammation as a typical feature of obesity. In particular, extra virgin olive oil (EVOO) is one of the most important functional foods exerting, among others, an anti-inflammatory activity not only due to its major (monounsaturated fatty acids) but also to its minor (phenolics) components, as reported in the last years. However, only a limited number of studies were performed on pediatric population, and even fewer are those focusing on EVOO phenolics that investigate the correlation of the chemical characterization with the biological function. Thus, starting from our

Indexed as

anti-inflammatory activityextra virgin olive oil (EVOO)factor analysispediatric obesityperipheral blood mononuclear cells (PBMCs)secoiridoidstandem mass spectrometry

Identifiers

PMID36386923
PMCPMC9643887
OpenAlexW4307349460

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.