Evidence map›Paper›PMID 36386696›Full record

ArticleFrontiers in microbiology2022

Sex hormones influence the intestinal microbiota composition in mice.

Yi Wu, Xinxin Peng, Xiaoya Li, Dandan Li, Zhoujin Tan, Rong Yu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 89 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Frontiers in veterinary science · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Microbiology spectrum · 2025
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yi WuCollege of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, China.
Xinxin PengDepartment of Pediatrics, The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, China.
Xiaoya LiCollege of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, China.
Dandan LiCollege of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, China.
Zhoujin TanCollege of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, China.
Rong YuCollege of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, China.
Hunan University of Traditional Chinese Medicine · CNFirst Affiliated Hospital of Hunan University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sex hormone secretion difference is one of the main reasons for sexually dimorphic traits in animals, which affects the dimorphism of the intestinal microbiota; however, their interaction is still unknown. Intestinal mucosa-associated microbiota (MAM) and intestinal luminal content microbiota (LM) belong to two different habitats according to the difference in interactions between bacteria and host intestinal epithelium/nutrients. To clarify the sexually dimorphic characteristics of MAM and LM and their correlation with sex hormones, 12 specific pathogen-free (SPF) Kunming mice from the same nest were fed separately according to sex. After 8 weeks, samples from the male intestinal mucosa group (MM group), the female intestinal mucosa group (FM group), the male intestinal content group (MC group), and the female intestinal content group (FC group) were collected and then, the next-generation sequencing of 16S ribosomal ribonucleic acid (rRNA) gene was performed. Our results showed that the sexual dimorphism of MAM was more obvious than that of LM and the relative abundance of

Indexed as

gender-associated diseasesintestinal luminal content microbiotaintestinal mucosa-associated microbiotasex dimorphism traitssex hormones

Identifiers

PMID36386696
PMCPMC9659915
OpenAlexW4307870679

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.