Evidence map›Paper›PMID 36386683›Full record

ArticleFrontiers in microbiology2022

Novel quorum sensing inhibitor Echinatin as an antibacterial synergist against

Yu-Bin Bai, Meng-Yan Shi, Wei-Wei Wang, Ling-Yu Wu, Yu-Ting Bai, Bing Li, Xu-Zheng Zhou, Ji-Yu Zhang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Inhibition of Shiga Toxin 2 forCurrent medicinal chemistry · 2026
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  6. Study on the antibacterial effect of the new anti-biofilm inhibitor ICAC onFrontiers in cellular and infection microbiology · 2025
    Article
  7. Significance of Chalcone Scaffolds in Medicinal Chemistry.Topics in current chemistry (Cham) · 2024
    Review
  8. Review
  9. Review
  10. Kaempferol restores the susceptibility of ESBLsFrontiers in microbiology · 2024
    Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yu-Bin BaiKey Laboratory of New Animal Drug Project of Gansu Province, Lanzhou, China.
Meng-Yan ShiKey Laboratory of New Animal Drug Project of Gansu Province, Lanzhou, China.
Wei-Wei WangKey Laboratory of New Animal Drug Project of Gansu Province, Lanzhou, China.
Ling-Yu WuKey Laboratory of New Animal Drug Project of Gansu Province, Lanzhou, China.
Yu-Ting BaiKey Laboratory of New Animal Drug Project of Gansu Province, Lanzhou, China.
Bing LiKey Laboratory of New Animal Drug Project of Gansu Province, Lanzhou, China.
Xu-Zheng ZhouKey Laboratory of New Animal Drug Project of Gansu Province, Lanzhou, China.
Ji-Yu ZhangKey Laboratory of New Animal Drug Project of Gansu Province, Lanzhou, China.
Chinese Academy of Agricultural Sciences · CNLanzhou Institute of Husbandry and Pharmaceutical Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new antibacterial strategy based on inhibiting bacterial quorum sensing (QS) has emerged as a promising method of attenuating bacterial pathogenicity and preventing bacterial resistance to antibiotics. In this study, we screened Echinatin (Ech) with high-efficiency anti-QS from 13 flavonoids through the AI-2 bioluminescence assay. Additionally, crystal violet (CV) staining combined with confocal laser scanning microscopy (CLSM) was used to evaluate the effect of anti-biofilm against

Indexed as

antibacterial synergistbiofilmEchinatinEPSEscherichia coliinhibitormotilityquorum sensing

Identifiers

PMID36386683
PMCPMC9663819
OpenAlexW4307855432

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.