Evidence map›Paper›PMID 36386600›Full record

ArticleIBRO neuroscience reports2022

Genetic loss of norepinephrine does not alter adult hippocampal neurogenesis in dopamine beta-hydroxylase deficient mice.

Darshana Kapri, Krishna C Vadodaria, Karen S Rommelfanger, Yvonne E Ogbonmwan, L Cameron Liles, Kimberly A Fernandes-Thomas, Sonali S Salvi, Basma F A Husain, David Weinshenker, Vidita A Vaidya

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in IBRO neuroscience reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Darshana KapriDepartment of Biological Sciences, Tata Institute of Fundamental Research, Mumbai 400005, India.
Krishna C VadodariaDepartment of Biological Sciences, Tata Institute of Fundamental Research, Mumbai 400005, India.
Karen S RommelfangerDepartment of Human Genetics, Emory University, Atlanta, GA 30322, USA.
Yvonne E OgbonmwanDepartment of Human Genetics, Emory University, Atlanta, GA 30322, USA.
L Cameron LilesDepartment of Human Genetics, Emory University, Atlanta, GA 30322, USA.
Kimberly A Fernandes-ThomasDepartment of Biological Sciences, Tata Institute of Fundamental Research, Mumbai 400005, India.
Sonali S SalviDepartment of Biological Sciences, Tata Institute of Fundamental Research, Mumbai 400005, India.
Basma F A HusainDepartment of Biological Sciences, Tata Institute of Fundamental Research, Mumbai 400005, India.
David WeinshenkerDepartment of Human Genetics, Emory University, Atlanta, GA 30322, USA.
Vidita A VaidyaDepartment of Biological Sciences, Tata Institute of Fundamental Research, Mumbai 400005, India.
Tata Institute of Fundamental Research · INEmory University · US

Funding

Mechanisms underlying selective vulnerability of locus coeruleus neurons in Alzheimer's diseaseRF1AG061175 · NIA · EMORY UNIVERSITY · PI KANG, SEONG SU, WEINSHENKER, DAVID · 2019 to 2019
$2.8M
Contribution of neuromelanin to selective vulnerability of locus coeruleus neurons in Alzheimer's diseaseRF1AG079199 · NIA · EMORY UNIVERSITY · PI WEINSHENKER, DAVID · 2022 to 2024
$1.6M
Contribution of neuromelanin to selective vulnerability of locus coeruleus neurons in Alzheimer's diseaseR01AG079199 · NIA · EMORY UNIVERSITY · PI DAVID WEINSHENKER · 2025 to 2026
$1.0M
NIA NIH HHS R01 AG079199NIA NIH HHS RF1 AG061175NIA NIH HHS RF1 AG079199
6 · The paper itself

Abstract

Norepinephrine (NE), and specific adrenoceptors, have been reported to influence distinct aspects of adult hippocampal neurogenesis, including latent stem cell activation, progenitor proliferation, and differentiation. These findings are predominantly based on the use of pharmacological approaches in both

Indexed as

BrdUDbh knockout miceDoublecortinDSP-4Hippocampal progenitorProliferation

Identifiers

PMID36386600
PMCPMC9643407
OpenAlexW4307423404

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.