Evidence map›Paper›PMID 36386414›Full record

ArticleInfection and drug resistance2022

Polymorphisms in the K13-Propeller Gene in Artemisinin-Resistant

Shaoqin Zheng, Yuan Liang, Zhaojia Wang, Min Liu, Yingyi Chen, Ying Ai, Wenfeng Guo, Guoming Li, Yueming Yuan, Zhiyong Xu and 6 more

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Shaoqin Zheng *Artemisinin Research Center, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Yuan Liang *Science and Technology Institute, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Zhaojia WangArtemisinin Research Center, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Min LiuArtemisinin Research Center, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Yingyi ChenArtemisinin Research Center, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Ying AiArtemisinin Research Center, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Wenfeng GuoArtemisinin Research Center, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Guoming LiArtemisinin Research Center, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Yueming YuanArtemisinin Research Center, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Zhiyong XuScience and Technology Institute, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Wanting WuArtemisinin Research Center, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Xinan HuangArtemisinin Research Center, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Zhibing WuThe First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Qin XuArtemisinin Research Center, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Jianping SongArtemisinin Research Center, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Changsheng DengArtemisinin Research Center, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Guangzhou University of Chinese Medicine · CNFirst Affiliated Hospital of Guangzhou University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Artemisinin-based combination therapies (ACTs) act as first-line antimalarial drugs and play a crucial role in the successful control of Methods: In this study, we have successfully produced artemisinin- and piperaquine-resistant Results: The resistance index of Conclusion: Our data show that artemisinin is less susceptible to severe resistance compared with other antimalarial drugs. In addition, mutation on

Indexed as

artemisinin resistancemalariaP. berghei K13 genePlasmodium berghei

Identifiers

PMID36386414
PMCPMC9653030
OpenAlexW4308592101

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.