Evidence map›Paper›PMID 36386378›Full record

ArticleFrontiers in cardiovascular medicine2022

Left ventricular remodeling following aortic root and ascending aneurysm repair.

Ignas B Houben, Angel K Y Chu, Bo Yang, Karen M Kim, Shinichi Fukuhara, Joost A van Herwaarden, Frans L Moll, David A Nordsletten, C Alberto Figueroa, Nicholas S Burris and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Windkessel Preserving Aortic Stent Graft Attenuates Left Ventricular Remodelling after Thoracic Endovascular Aortic Repair in a Porcine Model.European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ignas B HoubenDepartment of Cardiac Surgery, University of Michigan, Ann Arbor, MI, United States.
Angel K Y ChuDepartment of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, United States.
Bo YangDepartment of Cardiac Surgery, University of Michigan, Ann Arbor, MI, United States.
Karen M KimDepartment of Cardiac Surgery, University of Michigan, Ann Arbor, MI, United States.
Shinichi FukuharaDepartment of Cardiac Surgery, University of Michigan, Ann Arbor, MI, United States.
Joost A van HerwaardenDepartment of Vascular Surgery, University Medical Center Utrecht, Utrecht, Netherlands.
Frans L MollDepartment of Vascular Surgery, University Medical Center Utrecht, Utrecht, Netherlands.
David A NordslettenDepartment of Cardiac Surgery, University of Michigan, Ann Arbor, MI, United States.
C Alberto FigueroaDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States.
Nicholas S BurrisDepartment of Radiology, University of Michigan, Ann Arbor, MI, United States.
Himanshu J PatelDepartment of Cardiac Surgery, University of Michigan, Ann Arbor, MI, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Adverse left ventricular remodeling due to a mismatch between stiffness of native aortic tissue and current polyester grafts may be under-recognized. This study was conducted to evaluate the impact of proximal aortic replacement on adverse remodeling of the left ventricle. Materials and methods: All aortic root and ascending aortic aneurysm patients were identified ( Results: The mean age was 60 ± 11 years (80% male). Beta-blocker use was significantly more frequent in the surgery group (89 vs. 57%, Conclusion: Proximal aortic repair with stiff polyester grafts was associated with increased LV mass in the first-year post-operative and may promote long-term adverse cardiac remodeling. Further studies should be considered to evaluate the competing effects of aortic aneurysm related mortality against risks of long-term graft induced aortic stiffening and the potential implications on current size thresholds for intervention.

Indexed as

aortic aneurysm (thoracic)aortic repairascending aortacomputed tomography angiogram (CTA)ventricular remodeling

Identifiers

PMID36386378
PMCPMC9640592

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.