Evidence map›Paper›PMID 36386351›Full record

ArticleFrontiers in cardiovascular medicine2022

Impaired heart rate variability in patients with arrhythmogenic cardiomyopathy: A multicenter retrospective study in China.

Baowei Zhang, Chunjiang Zhou, Jinqiu Liu, Jinlin Zhang, Chenyang Jiang, Min Tang, Jiaxi Xie, Yizhang Wu, Xin Xie, Xiaorong Li and 9 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 8 institutions in 1 country.

Baowei ZhangCenter of Cardiology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Chunjiang ZhouCenter of Cardiology, Shanghai East Hospital, Nanjing Medical University, Shanghai, China.
Jinqiu LiuDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Jinlin ZhangDepartment of Cardiology, Wuhan Asia Heart Hospital, Wuhan, China.
Chenyang JiangDepartment of Cardiology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Min TangDepartment of Cardiology, State Key Laboratory of Cardiovascular Disease, Cardiovascular Institute, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Jiaxi XieDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Yizhang WuCenter of Cardiology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Xin XieCenter of Cardiology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Xiaorong LiCenter of Cardiology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Jinbo YuCenter of Cardiology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Xuecheng WangCenter of Cardiology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Dian ChengCenter of Cardiology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Jian ZhouCenter of Cardiology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Zijun ChenCenter of Cardiology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Fenghua FanCenter of Cardiology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Xiujuan ZhouDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Aibin TaoDepartment of Cardiology, The Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.
Bing YangCenter of Cardiology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Shanghai East Hospital · CNNanjing Medical University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNDalian Medical University · CNJiangsu Province Hospital · CNJiangsu University · CNWuhan Asia Heart Hospital · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardiac sympathetic nerve system (SNS) might play an important role in arrhythmogenesis of arrhythmogenic cardiomyopathy (ACM). This study aims to assess the activity of cardiac SNS in ACM patients by heart rate variability (HRV), and to investigate its predictive value for sustained ventricular tachycardia (sVT). Methods: A total of 88 ACM patients and 65 sex- and age- matched healthy participants were enrolled. The time domain measures were used to evaluate the activity of cardiac SNS. An independent cohort with 48 ACM patients was as the validation cohort. Results: ACM patients had lower levels of standard deviation of all NN intervals (SDNN) [118.0 (90.3, 136.8) vs. 152.0 (132.5, 174.5) ms, Conclusion: The present study suggests that HRV is impaired in patients with ACM, and the SDNN level has a moderate value in risk stratification for sVT in ACM patients. In addition, the finding might provide new target for the further management of ACM with integrated traditional Chinese and western medicine.

Indexed as

arrhythmogenic cardiomyopathy (ACM)heart rate variabilitySDNNsympathetic nerve system (SNS)ventricular tachycardia (VT)

Identifiers

PMID36386351
PMCPMC9659603
OpenAlexW4307678546

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.