ArticleFrontiers in cardiovascular medicine2022
Predictors and long-term outcomes of heart block after transcatheter device closure of perimembranous ventricular septal defect.
Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- Atrioventricular Conduction Disturbance After Perimembranous Ventricular Septal Defect Closure.JACC. Case reports · 2026Article
- A Tissue-Compliant Shape-Memory Composite Membrane for Cardiac Occluders.Bioengineering (Basel, Switzerland) · 2026Article
- Distal Radial Access for Perimembranous Ventricular Septal Defect Closure.JACC. Case reports · 2026Article
- Transcatheter Closure of Ventricular Septal Defects after Upfront Transvenous Antegrade Cannulation from the Right Ventricle.Pediatric cardiology · 2026Article
- Percutaneous closure of perimembranous and infundibular ventricular septal defects: single-center experience in 203 patients with medium- and long-term follow-up.International journal of cardiology. Congenital heart disease · 2025Article
- Treatment strategies and prognosis of complete left bundle branch block after transcatheter closure of ventricular septal defect in pediatrics.BMC cardiovascular disorders · 2025Article
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Heart block is the most common and concerning complication associated with transcatheter device closure of perimembranous ventricular septal defect (pmVSD) and its occurrence remains a great challenge for device closure. Methods: Between June 2002 and June 2020, 1076 pediatric patients with pmVSD, who successfully underwent transcatheter device closure in our center, were enrolled in this cohort study, with a median follow-up of 64 months (range: 1 to 19 years). Results: Of 1076 patients, 234 (21.8%) developed postprocedural heart block, with right bundle branch block being the most common (74.8%), followed by left bundle branch block (16.2%), and atrioventricular block (5.6%). Complete atrioventricular block occurred in 5 cases, including 3 cases with permanent pacemaker implantation, 1 case with recovery to normal sinus rhythm, and 1 case with sudden cardiac death. Most patients (97.9%) developed heart block within 1 week of procedure. Finally, 138 cases returned to normal cardiac conduction. Multivariate logistic regression revealed that thin-waist occluders (odds ratio [OR]: 1.759; 95% confidence interval [CI]: 1.023 to 3.022; Conclusion: The outcome of postprocedural heart block is favorable in most cases. Oversized devices and thin-waist occluders should be avoided. Placement of the left disk of the device should into the aneurysmal tissue is highly recommended.
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