Evidence map›Paper›PMID 36386228›Full record

ArticleFrontiers in pharmacology2022

CD82 attenuates TGF-β1-mediated epithelial-mesenchymal transition by blocking smad-dependent signaling in ARPE-19 cells.

Hyesook Lee, Jung-Hwa Han, Yun Jeong Kang, Hyun Hwangbo, Aeseon Yoon, Hyung-Sik Kim, Dongjun Lee, Soo Yong Lee, Byung Hyun Choi, Jae-Joon Kim and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Hyesook LeeDepartment of Convergence Medicine, Pusan National University School of Medicine, Yangsan, South Korea.
Jung-Hwa HanDepartment of Convergence Medicine, Pusan National University School of Medicine, Yangsan, South Korea.
Yun Jeong KangDepartment of Convergence Medicine, Pusan National University School of Medicine, Yangsan, South Korea.
Hyun HwangboDepartment of Biochemistry, Dong-eui University College of Korean Medicine, Busan, South Korea.
Aeseon YoonDepartment of Convergence Medicine, Pusan National University School of Medicine, Yangsan, South Korea.
Hyung-Sik KimDepartment of Oral Biochemistry, Dental and Life Science Institute, School of Dentistry, Pusan National University, Yangsan, South Korea.
Dongjun LeeDepartment of Convergence Medicine, Pusan National University School of Medicine, Yangsan, South Korea.
Soo Yong LeeDivision of Cardiology, Department of Internal Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, South Korea.
Byung Hyun ChoiDivision of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, South Korea.
Jae-Joon KimMedical Oncology and Hematology, Department of Internal Medicine, Pusan National University Yangsan Hospital, Yangsan, South Korea.
Seo Rin KimDepartment of Nephrology and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, South Korea.
Yung Hyun ChoiDepartment of Biochemistry, Dong-eui University College of Korean Medicine, Busan, South Korea.
Jin HurDepartment of Convergence Medicine, Pusan National University School of Medicine, Yangsan, South Korea.
Pusan National University · KRPusan National University Yangsan Hospital · KRDong-Eui University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In retinal pigment epithelial (RPE) cells, transforming growth factor-beta (TGF-β) plays a critical role in epithelial-mesenchymal transition (EMT), which contributes to various fibrotic retinal disorders. In the present study, we investigated the effect of recombinant human cluster of differentiation 82 (

Indexed as

epithelial-mesenchymal transition (EMT)fibrotic retinal disordersrecombinant human cluster of differentiation 82 (rhCD82)retinal pigment epithelial (RPE)transforming growth factor-beta (TGF-β)

Identifiers

PMID36386228
PMCPMC9640495
OpenAlexW4307372411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.