Evidence map›Paper›PMID 36386221›Full record

ReviewFrontiers in pharmacology2022

Pharmacologic therapies of ARDS: From natural herb to nanomedicine.

Linlin Meng, Ximing Liao, Yuanyuan Wang, Liangzhi Chen, Wei Gao, Muyun Wang, Huiling Dai, Na Yan, Yixuan Gao, Xu Wu and 2 more

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Multipotent mesenchymal stromal/stem cell-based therapies for acute respiratory distress syndrome: current progress, challenges, and future frontiers.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2024
    Review
  10. Article
  11. Article
  12. siRNA-MediatedInternational journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Linlin MengShandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
Ximing LiaoDepartment of Critical Care Medicine, Shanghai East Hospital, School of medicine, Tongji University, China.
Yuanyuan WangDepartment of Critical Care Medicine, Shanghai East Hospital, School of medicine, Tongji University, China.
Liangzhi ChenShandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
Wei GaoDepartment of Critical Care Medicine, Shanghai East Hospital, School of medicine, Tongji University, China.
Muyun WangDepartment of Critical Care Medicine, Shanghai East Hospital, School of medicine, Tongji University, China.
Huiling DaiDepartment of Critical Care Medicine, Shanghai East Hospital, School of medicine, Tongji University, China.
Na YanShandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
Yixuan GaoDepartment of Gynecology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Xu WuDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Kun WangDepartment of Critical Care Medicine, Shanghai East Hospital, School of medicine, Tongji University, China.
Qinghua LiuDepartment of Critical Care Medicine, Shanghai East Hospital, School of medicine, Tongji University, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute respiratory distress syndrome (ARDS) is a common critical illness in respiratory care units with a huge public health burden. Despite tremendous advances in the prevention and treatment of ARDS, it remains the main cause of intensive care unit (ICU) management, and the mortality rate of ARDS remains unacceptably high. The poor performance of ARDS is closely related to its heterogeneous clinical syndrome caused by complicated pathophysiology. Based on the different pathophysiology phases, drugs, protective mechanical ventilation, conservative fluid therapy, and other treatment have been developed to serve as the ARDS therapeutic methods. In recent years, there has been a rapid development in nanomedicine, in which nanoparticles as drug delivery vehicles have been extensively studied in the treatment of ARDS. This study provides an overview of pharmacologic therapies for ARDS, including conventional drugs, natural medicine therapy, and nanomedicine. Particularly, we discuss the unique mechanism and strength of nanomedicine which may provide great promises in treating ARDS in the future.

Indexed as

acute lung injuryacute respiratory distress syndromedrug deliverynanomedicinenatural herbpharmacology

Identifiers

PMID36386221
PMCPMC9651133

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.