Evidence map›Paper›PMID 36386220›Full record

ArticleFrontiers in pharmacology2022

Cryptotanshinone protects skin cells from ultraviolet radiation-induced photoaging

Keke Guo, Run Liu, Rongrong Jing, Lusheng Wang, Xuenan Li, Kaini Zhang, Mengli Fu, Jiabin Ye, Zhenlin Hu, Wengang Zhao and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
10.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Toxicological Assessment and Dual Protective Roles ofJournal of fungi (Basel, Switzerland) · 2026
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  10. Review
  11. Role of Mitochondrial Dynamics in Skin Homeostasis: An Update.International journal of molecular sciences · 2025
    Review
  12. Frontiers in pharmacology · 2025
    Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Natural Modulators of Key Signaling Pathways in Skin Inflammageing.Clinical, cosmetic and investigational dermatology · 2024
    Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Keke GuoCollege of Life and Environmental Sciences, Wenzhou University, Wenzhou, China.
Run LiuZhiyuan College, Shanghai Jiao Tong University, Shanghai, China.
Rongrong JingCollege of Life and Environmental Sciences, Wenzhou University, Wenzhou, China.
Lusheng WangCollege of Life and Environmental Sciences, Wenzhou University, Wenzhou, China.
Xuenan LiDepartment of Pharmacy, Zhoupu Hospital, Shanghai, China.
Kaini ZhangCollege of Life and Environmental Sciences, Wenzhou University, Wenzhou, China.
Mengli FuCollege of Life and Environmental Sciences, Wenzhou University, Wenzhou, China.
Jiabin YeCollege of Life and Environmental Sciences, Wenzhou University, Wenzhou, China.
Zhenlin HuSchool of Medicine, Shanghai University, Shanghai, China.
Wengang ZhaoInstitute of Life Sciences, Wenzhou University, Wenzhou, China.
Nuo XuCollege of Life and Environmental Sciences, Wenzhou University, Wenzhou, China.
Wenzhou University · CNShanghai Jiao Tong University · CNShanghai University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The integrity of skin tissue structure and function plays an important role in maintaining skin rejuvenation. Ultraviolet (UV) radiation is the main environmental factor that causes skin aging through photodamage of the skin tissue. Cryptotanshinone (CTS), an active ingredient mianly derived from the

Indexed as

apoptosiscryptotanshinone (CTS)mitochondrial dysfunctionmitochondrial synthesisoxidative stressphotoagingultraviolet (UV) radiation

Identifiers

PMID36386220
PMCPMC9640529
OpenAlexW4307373407

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.