Evidence map›Paper›PMID 36386177›Full record

ArticleFrontiers in pharmacology2022

Differentiation and on axon-guidance chip culture of human pluripotent stem cell-derived peripheral cholinergic neurons for airway neurobiology studies.

P A Goldsteen, A M Sabogal Guaqueta, P P M F A Mulder, I S T Bos, M Eggens, L Van der Koog, J T Soeiro, A J Halayko, K Mathwig, L E M Kistemaker and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. The Role of the Nervous System in Lung Disease.Current neurology and neuroscience reports · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

P A GoldsteenDepartment of Molecular Pharmacology, University of Groningen, Groningen, Netherlands.
A M Sabogal GuaquetaDepartment of Molecular Pharmacology, University of Groningen, Groningen, Netherlands.
P P M F A MulderDepartment of Pharmaceutical Analysis, University of Groningen, Groningen, Netherlands.
I S T BosDepartment of Molecular Pharmacology, University of Groningen, Groningen, Netherlands.
M EggensDepartment of Molecular Pharmacology, University of Groningen, Groningen, Netherlands.
L Van der KoogDepartment of Molecular Pharmacology, University of Groningen, Groningen, Netherlands.
J T SoeiroDepartment of Molecular Pharmacology, University of Groningen, Groningen, Netherlands.
A J HalaykoDepartment of Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB, Canada.
K MathwigDepartment of Pharmaceutical Analysis, University of Groningen, Groningen, Netherlands.
L E M KistemakerDepartment of Molecular Pharmacology, University of Groningen, Groningen, Netherlands.
E M J VerpoorteDepartment of Pharmaceutical Analysis, University of Groningen, Groningen, Netherlands.
A M DolgaDepartment of Molecular Pharmacology, University of Groningen, Groningen, Netherlands.
R GosensDepartment of Molecular Pharmacology, University of Groningen, Groningen, Netherlands.
University of Groningen · NLUniversity of Manitoba · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Airway cholinergic nerves play a key role in airway physiology and disease. In asthma and other diseases of the respiratory tract, airway cholinergic neurons undergo plasticity and contribute to airway hyperresponsiveness and mucus secretion. We currently lack human

Indexed as

asthmacholinergicneuronorgan-on-chipstem cell

Identifiers

PMID36386177
PMCPMC9651921
OpenAlexW4307701952

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.