Evidence map›Paper›PMID 36386155›Full record

ArticleFrontiers in pharmacology2022

Quercetin Suppresses Human Glioblastoma Migration and Invasion via GSK3β/β-catenin/ZEB1 Signaling Pathway.

Bo Chen, Xiaoli Li, Lihong Wu, Duanfang Zhou, Yi Song, Limei Zhang, Qiuya Wu, Qichen He, Gang Wang, Xu Liu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Bo ChenDepartment of Pharmacology, College of Pharmacy, Chongqing Medical University, Chongqing, China.
Xiaoli LiDepartment of Pharmacology, College of Pharmacy, Chongqing Medical University, Chongqing, China.
Lihong WuDepartment of Pharmacology, College of Pharmacy, Chongqing Medical University, Chongqing, China.
Duanfang ZhouDepartment of Pharmacology, College of Pharmacy, Chongqing Medical University, Chongqing, China.
Yi SongDepartment of Pharmacology, College of Pharmacy, Chongqing Medical University, Chongqing, China.
Limei ZhangDepartment of Pharmacology, College of Pharmacy, Chongqing Medical University, Chongqing, China.
Qiuya WuDepartment of Pharmacology, College of Pharmacy, Chongqing Medical University, Chongqing, China.
Qichen HeDepartment of Pharmacology, College of Pharmacy, Chongqing Medical University, Chongqing, China.
Gang WangDepartment of Pharmacology, College of Pharmacy, Chongqing Medical University, Chongqing, China.
Xu LiuDepartment of Pharmacology, College of Pharmacy, Chongqing Medical University, Chongqing, China.
Hui HuDepartment of Pharmacology, College of Pharmacy, Chongqing Medical University, Chongqing, China.
Weiying ZhouDepartment of Pharmacology, College of Pharmacy, Chongqing Medical University, Chongqing, China.
Chongqing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High invasiveness is a biological and clinical characteristic of glioblastoma and predicts poor prognosis of patients. Quercetin, a natural flavonoid compound, exhibits anticancer activity. However, we have a limited understanding of the possible underlying mechanism of quercetin in glioblastoma. In this study, we investigated the anticancer effect of quercetin in human glioblastoma cells. Our results showed that quercetin markedly suppressed the viability of glioblastoma cells

Indexed as

epithelial-like mesenchymal transitionglioblastomaGSK3β/β-catenin/ZEB1 signalingmetastasisquercetin

Identifiers

PMID36386155
PMCPMC9663482
OpenAlexW4308006479

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.