Evidence map›Paper›PMID 36385753›Full record

ArticleFrontiers in molecular neuroscience2022

Combination effect between gut microbiota and traditional potentially modifiable risk factors for first-ever ischemic stroke in Tujia, Miao and Han populations in China.

Na Zhang, Haoren Wang, Xiaolei Wang, Mengyuan Tian, Yong Tian, Qi Li, Chengcai Liang, Xiaowei Peng, Jian Ding, Xinrui Wu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Association between gut microbiome and intracerebral hemorrhage based on genome-wide association study data.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Na ZhangHunan Provincial Key Laboratory of Clinical Epidemiology, Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, China.
Haoren WangHunan Provincial Key Laboratory of Clinical Epidemiology, Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, China.
Xiaolei WangHunan Provincial Key Laboratory of Clinical Epidemiology, Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, China.
Mengyuan TianHunan Provincial Key Laboratory of Clinical Epidemiology, Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, China.
Yong TianDepartment of Neurology, The First Affiliated Hospital of Jishou University, Xiangxi, China.
Qi LiDepartment of Planned Immunity, Xiangxi Center for Disease Prevention and Control, Xiangxi, China.
Chengcai LiangDepartment of Neurology, The First Affiliated Hospital of Jishou University, Xiangxi, China.
Xiaowei PengDepartment of Neurology, The First Affiliated Hospital of Jishou University, Xiangxi, China.
Jian DingDepartment of Geriatric Rehabilitation, Hunan Provincial Rehabilitation Hospital, Changsha, China.
Xinrui WuHunan Provincial Key Laboratory of Clinical Epidemiology, Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, China.
Hongzhuan TanHunan Provincial Key Laboratory of Clinical Epidemiology, Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, China.
Central South University · CNJishou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

China has had explosive growth in ischemic stroke (IS) burden with significant ethnic and geographic disparities. The aim of this study was to explore the possible combination effect between gut microbiota and traditional potentially modifiable risk factors for IS among two ethnic minorities (Tujia and Miao) and the Han population. Herein, we first used the 16 S rRNA sequencing to compare the gut microbial compositions of 82 patients with first-ever IS vs. 82 normal controls (NCs) among Han, Tujia, and Miao people between 1 May 2018 and 30 April 2019, from Xiangxi Tujia and Miao Autonomous Prefecture in China. An additive model was used to study the interaction between traditional risk factors and gut microbiota with R software. Linear discriminant analysis (LDA) and LDA effect size (LEfSe) results showed that the identified key gut microbiota's taxonomic composition varied in different ethnicity between the IS patients and NCs. Furthermore, families

Indexed as

additive interactiongut microbiotaischemic strokepreventionrisk factor

Identifiers

PMID36385753
PMCPMC9641726
OpenAlexW4307201162

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.