ReviewOrthopedic research and reviews2022
Current Concept Review: Risk Factors for Infection Following Open Fractures.
Review in Orthopedic research and reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed.
- Effects of hypochlorous acid, povidone-iodine, and Carrel-Dakin solution irrigation on open fracture healing: a rat femur model.Journal of orthopaedic surgery and research · 2026Article
- Open Fractures in Polytrauma and Non-Polytrauma Patients: Outcomes and Predictive Factors in a Level III Trauma Center.Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca · 2026Article
- The First Decisions Matter: Integrating Stability, Biology, and Reconstruction in Open Fracture Care.Journal of orthopaedic case reports · 2026Article
- Early prophylactic antibiotics effect on infection rate in blunt open fractures.Journal of orthopaedic surgery and research · 2026Article
- Circulating CD38Scientific reports · 2026Article
- Surgical debridement of low velocity ballistic traumatic arthrotomy did not reduce rates of early wound infection or septic arthritis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026Article
- Basic science and current management for fracture-related infections.OTA international : the open access journal of orthopaedic trauma · 2025Article
- Outcomes of Distal Radius Fractures: A Comparison Between Fellowship-Trained Trauma and Hand Orthopaedic Surgeons.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025Article
- Review
- Aeromonas hydrophila-related fulminant necrotizing fasciitis and arterial embolization after plaster placement in Gustilo I distal radius fracture: a case report and literature review.BMC musculoskeletal disorders · 2025Review
- Revisiting the OTA-OFC: a systematic review of open fracture classification studies since 2010.OTA international : the open access journal of orthopaedic trauma · 2025Article
- Comparing piperacillin/tazobactam to current guidelines for the treatment of open fractures: A systematic review.Journal of orthopaedics · 2025Review
- Return to Sport or Military Duty After Lower Extremity Open Fracture: Systematic Review of Athletes and Active Military.Foot & ankle orthopaedics · 2025Article
- Evaluation of Institutional Prophylactic Open Fracture Antibiotic Guidelines on Infection Development.Cureus · 2025Article
- Current Strategies in the Prevention and Management of Infection in Open Fractures.Journal of orthopaedics and sports medicine · 2025Article
- Article
- Severe soft tissue injuries in multiple trauma patients-a challenge we can meet? A matched-pair analysis from the TraumaRegister DGUFrontiers in medicine · 2025Article
- RETROSPECTIVE ANALYSIS OF THE IMPACT OF NEGATIVE PRESSURE WOUND THERAPY ON COMPLICATIONS OF DELAYED COVERAGE OF IIIB EXPOSED TIBIAL FRACTURES.Acta ortopedica brasileira · 2025Article
- Article
- Risk of infection and conversion time from external to definitive fixation in open tibial fracture.Journal of orthopaedic surgery and research · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Infection following open fracture is a significant source of morbidity and mortality. Therefore, a central tenet of treatment is to minimize the risk of infection. The initial risk of infection is determined by wound characteristics, such as size, soft tissue coverage, vascular injury, and contamination. While no consensus exists on optimal antibiotic regimen, early administration of prophylactic antibiotics, within an hour of injury, when possible, has been shown definitively to decrease the risk of infection. Infection risk is further reduced by early irrigation with normal saline and aggressive debridement of devitalized tissue. Patient factors that increase risk of infection following open fracture include diabetes mellitus, smoking, male gender, and lower extremity fracture.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.