ArticleCommunications biology2022
Complexity of modular neuromuscular control increases and variability decreases during human locomotor development.
Article in Communications biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 32 citations in OpenAlex.
- Limb-specific modulation of muscle synergies and segmental coordination during curved running.Experimental brain research · 2026Article
- Infants' spontaneous movements explore arm dynamics.Communications biology · 2026Article
- Task complexity amplifies spatial asymmetry of muscle synergy plasticity in chronic stroke survivors.Journal of neuroengineering and rehabilitation · 2026Article
- Muscle synergy characteristics during hands-and-knees crawling in children aged 4-6 years.PloS one · 2026Article
- Real-time approach to evaluate spinal cord topography of motor pool activation during gait.Frontiers in bioengineering and biotechnology · 2026Article
- The role of independent walking in the maturation of the spinal locomotor output in children with cerebral palsy.Frontiers in physiology · 2026Article
- Functional symmetrization of neuromotor modules during locomotor development in human infants.Communications biology · 2025Article
- A single low-dimensional neural component of spinal motor neuron activity explains force generation across repetitive isometric tasks.iScience · 2025Article
- Motor synergy and energy efficiency emerge in whole-body locomotion learning.Scientific reports · 2025Article
- Muscle responses to limb block during spontaneous movements in infants.Frontiers in neuroscience · 2025Article
- Leg-specific modulation of muscle synergies during Tai Chi heel kick in elite athletes.Frontiers in physiology · 2025Article
- Increased trial-to-trial similarity and reduced temporal overlap of muscle synergy activation coefficients manifest during learning and with increasing movement proficiency.Scientific reports · 2024Article
- Program with last minute abstracts of the Padua Days on Muscle and Mobility Medicine, 27 February - 2 March, 2024 (2024Pdm3).European journal of translational myology · 2024Article
- Design of Low-Cost Modular Bio-Inspired Electric-Pneumatic Actuator (EPA)-Driven Legged Robots.Biomimetics (Basel, Switzerland) · 2024Article
- Motor patterns of patients with spinal muscular atrophy suggestive of sensory and corticospinal contributions to the development of locomotor muscle synergies.Journal of neurophysiology · 2024Article
- Evaluation of EMG patterns in children during assisted walking in the exoskeleton.Frontiers in neuroscience · 2024Article
- Five Padua days on muscle and mobility medicine (2024Pdm3) 27 February - 2 March, 2024 at Hotel Petrarca, Thermae of Euganean Hills, Padua, and San Luca Hall, Prato della Valle, Padua, Italy.European journal of translational myology · 2023Article
- Learning to Move in a Changing Body in a Changing World.Integrative and comparative biology · 2023Article
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Corrections and comments
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Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
When does modular control of locomotion emerge during human development? One view is that modularity is not innate, being learnt over several months of experience. Alternatively, the basic motor modules are present at birth, but are subsequently reconfigured due to changing brain-body-environment interactions. One problem in identifying modular structures in stepping infants is the presence of noise. Here, using both simulated and experimental muscle activity data from stepping neonates, infants, preschoolers, and adults, we dissect the influence of noise, and identify modular structures in all individuals, including neonates. Complexity of modularity increases from the neonatal stage to adulthood at multiple levels of the motor infrastructure, from the intrinsic rhythmicity measured at the level of individual muscles activities, to the level of muscle synergies and of bilateral intermuscular network connectivity. Low complexity and high variability of neuromuscular signals attest neonatal immaturity, but they also involve potential benefits for learning locomotor tasks.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.