Evidence map›Paper›PMID 36385503›Full record

ArticlePhysiological reports2022

Does sex interact with the 2D:4D ratio or adult circulating hormones on the estimated glomerular filtration rate? A cross-sectional study in Ghana.

Moses Banyeh, Kervin Edinam Zogli, Hisham Alhassan Osumanu, Lawrence Obeng, Tuah Kwabena Acheampong, Clement Binwatin Dagungong, Elizabeth Bayor, Nafiu Amidu

Abstract read
In one paragraph

Article in Physiological reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Moses BanyehDepartment of Biomedical Laboratory Science, University for Development Studies, Tamale, Ghana.ORCID 0000-0003-3594-6077
Kervin Edinam ZogliDepartment of Biomedical Laboratory Science, University for Development Studies, Tamale, Ghana.
Hisham Alhassan OsumanuDepartment of Biomedical Laboratory Science, University for Development Studies, Tamale, Ghana.
Lawrence ObengDepartment of Biomedical Laboratory Science, University for Development Studies, Tamale, Ghana.
Tuah Kwabena AcheampongDepartment of Biomedical Laboratory Science, University for Development Studies, Tamale, Ghana.
Clement Binwatin DagungongDepartment of Biomedical Laboratory Science, University for Development Studies, Tamale, Ghana.
Elizabeth BayorDepartment of Biomedical Laboratory Science, University for Development Studies, Tamale, Ghana.
Nafiu AmiduDepartment of Biomedical Laboratory Science, University for Development Studies, Tamale, Ghana.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 2D:4D ratio is the putative marker of prenatal hormone exposure and has been suggested as a correlate of adult circulating testosterone and estrogen. The study aimed to determine whether sexual dimorphism in the estimated glomerular filtration rate (eGFR) can be partly explained by the 2D:4D ratio or adult circulating testosterone or estrogen. The study was cross-sectional from June to December 2021 at the University for Development Studies. The study involved 206 healthy adults (Female = 93, Male = 113) between 18 and 30 years. The 2D:4D ratio was measured using computer-assisted analysis. Venous blood samples were collected and analyzed for testosterone, estradiol and creatinine using the ELISA technique and routine biochemical analysis. The adjusted eGFR was calculated using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) creatinine equation (2021). The eGFR and the testosterone-to-estradiol ratio (TT:E

Indexed as

FingersRenal Insufficiency, ChronicAdultCreatinineCross-Sectional StudiesEstradiolEstrogensFemaleGhanaGlomerular Filtration RateHumansMalePregnancyTestosteroneCreatinineEstradiolEstrogensTestosteroneadultGhanaglomerular filtration ratehumansthe 2D:4D ratio

Identifiers

PMID36385503
PMCPMC9669620

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.