ArticleSleep2023
Sleep architecture is associated with core symptom severity in autism spectrum disorder.
Article in Sleep, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 27 citations in OpenAlex.
- Wireless Electroencephalography in Research on Children With Developmental Disabilities: Scoping Review.Journal of medical Internet research · 2026Article
- Exploring the Relationship Between Age of Nap Cessation, Screen-Positive Autism Spectrum Disorder Traits and Diagnosis of Attention-Deficit Hyperactivity Disorder.Journal of autism and developmental disorders · 2026Article
- Excitation/Inhibition Balance as a Mechanistic Link Between Sleep Disturbance and Autism Spectrum Disorder: A Bidirectional Framework.Alpha psychiatry · 2026Review
- Home Polysomnography in Children With Autism Spectrum Disorder: A Prospective Observational Study.Journal of sleep research · 2026Observational
- Aperiodic and periodic neural activity during sleep in autism spectrum disorders.BMC medicine · 2026Article
- Sleep and activity patterns in autism.Autism : the international journal of research and practice · 2026Article
- Association of glymphatic dysfunction, free water, white matter integrity and long-term memory performance in aging autistic adults.Molecular autism · 2026Article
- An open science resource for accelerating scalable digital health research in autism and other neurodevelopmental conditions.Nature neuroscience · 2026Article
- Sleep problems in autistic children and adolescents: an age-stratified approach.Frontiers in psychology · 2026Article
- Theta Activity at Sleep Onset in Children with Autism Spectrum Disorder.Journal of autism and developmental disorders · 2025Article
- Evaluating the effect of repetitive transcranial magnetic stimulation on sleep difficulties in children with autism spectrum disorder: a randomized controlled trial.Sleep advances : a journal of the Sleep Research Society · 2025Article
- Circadian activity and sleep architecture in autism spectrum disorder mouse model withFrontiers in sleep · 2025Article
- Spindle chirp and other sleep oscillatory features in young children with autism.Sleep medicine · 2024Article
- Polyphenols: Natural Food-Grade Biomolecules for the Treatment of Nervous System Diseases from a Multi-Target Perspective.Pharmaceuticals (Basel, Switzerland) · 2024Review
- Autism Across the Lifespan.Focus (American Psychiatric Publishing) · 2024Article
- Sleep and Autism: Current Research, Clinical Assessment, and Treatment Strategies.Focus (American Psychiatric Publishing) · 2024Article
- From macro to micro: slow-wave sleep and its pivotal health implications.Frontiers in sleep · 2024Review
- Spindle Chirp and other Sleep Oscillatory Features in Young Children with Autism.bioRxiv : the preprint server for biology · 2023Article
- Exploring the Relationship of Autism Spectrum Disorder Characteristics and Sleep Disturbances.Autism & developmental language impairmentsArticle
Corrections and comments
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
Abstract
STUDY
objectivesWhile caregiver-reported sleep disturbances are common in children and adolescents with autism spectrum disorder (['), few studies have measured objective sleep in ASD compared to controls, and their findings are mixed. We investigated (1) differences in sleep architecture, specifically slow-wave sleep (SWS) and rapid eye movement (REM) sleep, between ASD and typically developing controls (TD); and (2) if any observed differences in sleep were associated with core ASD symptoms.
methodsWe used ambulatory polysomnography (PSG) in 53 participants with ASD (ages 4-18) and 66 age-matched TD in their home sleeping environment. The primary outcome measures were SWS and REM sleep. Core behavioral ASD symptoms were assessed using the Autism Diagnostic Interview-Revised (ADI-R). Spectral power bands during sleep, and additional behavioral measures, were examined in exploratory analyses.
resultsCompared to TD, participants with ASD exhibited a higher SWS ratio and lower REM sleep ratio. Within the ASD group, higher SWS was associated with more severe symptoms on the Restricted, Repetitive, and Stereotyped Behaviors subscale of the ADI-R. No association was observed between REM sleep ratio and any ASD symptom.
conclusionsIncreased SWS and reduced REM sleep ratio differentiated ASD from TD. However, only increased SWS was associated with more severe core ASD symptoms. Increased SWS may reflect neuronal immaturity specific to ASD in this age group. These findings may inform the underlying mechanisms of clinical symptoms observed in children and adolescents with ASD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.