Evidence map›Paper›PMID 36385309›Full record

ArticleScientific reports2022

Birefringence-derived scleral artifacts in optical coherence tomography images of eyes with pathologic myopia.

Masahiro Miura, Shuichi Makita, Yoshiaki Yasuno, Atsuya Miki, Rei Nemoto, Hiroyuki Shimizu, Shinnosuke Azuma, Toshihiro Mino, Tatsuo Yamaguchi

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Masahiro MiuraDepartment of Ophthalmology, Ibaraki Medical Center, Tokyo Medical University, 3-20-1 Chuo, Ami, Inashiki, Ibaraki, 300395, Japan. m-miura@tokyo-med.ac.jp.
Shuichi MakitaComputational Optics Group, University of Tsukuba, Tsukuba, Japan.
Yoshiaki YasunoComputational Optics Group, University of Tsukuba, Tsukuba, Japan.
Atsuya MikiDepartment of Myopia Control Research, Aichi Medical University, Nagakute, Japan.
Rei NemotoDepartment of Ophthalmology, Ibaraki Medical Center, Tokyo Medical University, 3-20-1 Chuo, Ami, Inashiki, Ibaraki, 300395, Japan.
Hiroyuki ShimizuDepartment of Ophthalmology, Ibaraki Medical Center, Tokyo Medical University, 3-20-1 Chuo, Ami, Inashiki, Ibaraki, 300395, Japan.
Shinnosuke AzumaTopcon Corporation, Tokyo, Japan.
Toshihiro MinoTopcon Corporation, Tokyo, Japan.
Tatsuo YamaguchiTopcon Corporation, Tokyo, Japan.
Tokyo Medical University Ibaraki Medical Center · JPTopcon (Japan) · JPUniversity of Tsukuba · JPAichi Medical University · JP

Funding

Japan Science and Technology Agency JPMJCR2105Japan Science and Technology Agency JPMJMI18G8Japan Society for the Promotion of Science 21H01836Japan Society for the Promotion of Science 21K09684
6 · The paper itself

Abstract

We investigated birefringence-derived scleral artifacts in optical coherence tomography (OCT) images of eyes with pathologic myopia. This study included 76 eyes of 42 patients with pathologic myopia. Five sets of OCT B-scan images of the macula were obtained using commercial swept-source OCT. A dataset of prototype swept-source polarization-diversity OCT images was used to identify polarization-dependent OCT images (i.e., complex averaging of OCT signals from two polarization channels) and polarization-independent OCT images (i.e., intensity averaging of two OCT signals). Polarization-dependent OCT images and commercial OCT images were assessed for the presence of birefringence-derived artifacts by comparison with polarization-independent OCT images. Both polarization-dependent OCT images and commercial OCT images contained scleral vessel artifacts. Scleral vessel artifacts were present in 46 of 76 eyes (60.5%) imaged by polarization-dependent OCT and 17 of 76 eyes (22.4%) imaged by commercial OCT. The proportion of images that showed scleral vessel artifacts was significantly greater among polarization-dependent OCT images than among commercial OCT images (P < 0.001). Additionally, polarization-dependent OCT images showed low-intensity band artifacts. This study demonstrated the existence of birefringence-derived scleral artifacts in commercial OCT images and indicated that polarization-diversity OCT is an effective tool to evaluate the presence of these artifacts.

Indexed as

MyopiaTomography, Optical CoherenceArtifactsBirefringenceHumansSclera

Identifiers

PMID36385309
PMCPMC9669004
OpenAlexW4309332262

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.