Evidence map›Paper›PMID 36385275›Full record

ArticleScientific reports2022

Multiomics analysis couples mRNA turnover and translational control of glutamine metabolism to the differentiation of the activated CD4

Louise S Matheson, Georg Petkau, Beatriz Sáenz-Narciso, Vanessa D'Angeli, Jessica McHugh, Rebecca Newman, Haydn Munford, James West, Krishnendu Chakraborty, Jennie Roberts and 5 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Louise S MathesonImmunology Programme, The Babraham Institute, Babraham Research Campus, Cambridge, CB22 3AT, UK. louise.matheson@babraham.ac.uk.
Georg PetkauImmunology Programme, The Babraham Institute, Babraham Research Campus, Cambridge, CB22 3AT, UK.
Beatriz Sáenz-NarcisoImmunology Programme, The Babraham Institute, Babraham Research Campus, Cambridge, CB22 3AT, UK.
Vanessa D'AngeliImmunology Programme, The Babraham Institute, Babraham Research Campus, Cambridge, CB22 3AT, UK.
Jessica McHughImmunology Programme, The Babraham Institute, Babraham Research Campus, Cambridge, CB22 3AT, UK.
Rebecca NewmanImmunology Programme, The Babraham Institute, Babraham Research Campus, Cambridge, CB22 3AT, UK.
Haydn MunfordInstitute of Immunology and Immunotherapy, College of Medical and Dental Sciences, IBR, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
James WestCambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, CB2 0AW, UK.
Krishnendu ChakrabortyImmunology Programme, The Babraham Institute, Babraham Research Campus, Cambridge, CB22 3AT, UK.
Jennie RobertsInstitute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK.
Sebastian ŁukasiakImmunology Programme, The Babraham Institute, Babraham Research Campus, Cambridge, CB22 3AT, UK.
Manuel D Díaz-MuñozImmunology Programme, The Babraham Institute, Babraham Research Campus, Cambridge, CB22 3AT, UK.
Sarah E BellImmunology Programme, The Babraham Institute, Babraham Research Campus, Cambridge, CB22 3AT, UK.
Sarah DimeloeInstitute of Immunology and Immunotherapy, College of Medical and Dental Sciences, IBR, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Martin TurnerImmunology Programme, The Babraham Institute, Babraham Research Campus, Cambridge, CB22 3AT, UK. martin.turner@babraham.ac.uk.
Babraham Institute · GBUniversity of Birmingham · GBUniversity of Cambridge · GB

Funding

Biotechnology and Biological Sciences Research Council BBS/E/B/000C0427Medical Research Council MR/V011588/1Wellcome Trust 200823/Z/16/Z
6 · The paper itself

Abstract

The ZFP36 family of RNA-binding proteins acts post-transcriptionally to repress translation and promote RNA decay. Studies of genes and pathways regulated by the ZFP36 family in CD4

Indexed as

GlutamineKetoglutaric AcidsCD4-Positive T-LymphocytesRNA, MessengerT-LymphocytesGlutamineKetoglutaric AcidsRNA, Messenger

Identifiers

PMID36385275
PMCPMC9669047
OpenAlexW4309338377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.