Evidence map›Paper›PMID 36385167›Full record

ArticleMolecular psychiatry2023

Genetic nurture versus genetic transmission of risk for ADHD traits in the Norwegian Mother, Father and Child Cohort Study.

Jean-Baptiste Pingault, Wikus Barkhuizen, Biyao Wang, Laurie J Hannigan, Espen Moen Eilertsen, Elizabeth Corfield, Ole A Andreassen, Helga Ask, Martin Tesli, Ragna Bugge Askeland and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Molecular psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
7.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 59 citations in OpenAlex.

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  6. Indirect genetic effects of siblings.Journal of child psychology and psychiatry, and allied disciplines · 2026
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  16. Shared genetic architecture of brain age gap across 30 cohorts worldwide.medRxiv : the preprint server for health sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 2 countries.

Jean-Baptiste Pingault *Division of Psychology and Language Sciences, University College London, London, United Kingdom.
Wikus Barkhuizen *Division of Psychology and Language Sciences, University College London, London, United Kingdom. w.barkhuizen@ucl.ac.uk.ORCID 0000-0001-5170-1470
Biyao WangDivision of Psychology and Language Sciences, University College London, London, United Kingdom.
Laurie J HanniganNic Waals Institute, Lovisenberg Diaconal Hospital, Oslo, Norway.ORCID 0000-0003-3123-5411
Espen Moen EilertsenPROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.
Elizabeth CorfieldNic Waals Institute, Lovisenberg Diaconal Hospital, Oslo, Norway.ORCID 0000-0002-0119-157X
Ole A AndreassenNORMENT Centre, Institute of Clinical Medicine, University of Oslo and Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.ORCID 0000-0002-4461-3568
Helga AskDepartment of Mental Disorders, Norwegian Institute of Public Health, Oslo, Norway.ORCID 0000-0003-0149-5319
Martin TesliDepartment of Mental Disorders, Norwegian Institute of Public Health, Oslo, Norway.ORCID 0000-0001-7495-5545
Ragna Bugge AskelandDepartment of Mental Disorders, Norwegian Institute of Public Health, Oslo, Norway.
George Davey SmithMRC Integrative Epidemiology Unit (IEU), University of Bristol, Bristol, United Kingdom.ORCID 0000-0002-1407-8314
Camilla StoltenbergNorwegian Institute of Public Health, Oslo, Norway.ORCID 0000-0002-8747-1985
Neil M DaviesMRC Integrative Epidemiology Unit (IEU), University of Bristol, Bristol, United Kingdom.ORCID 0000-0002-2460-0508
Ted Reichborn-KjennerudDepartment of Mental Disorders, Norwegian Institute of Public Health, Oslo, Norway.ORCID 0000-0003-4653-0034
Eivind Ystrom *Department of Mental Disorders, Norwegian Institute of Public Health, Oslo, Norway.ORCID 0000-0003-4390-6171
Alexandra Havdahl *Nic Waals Institute, Lovisenberg Diaconal Hospital, Oslo, Norway.
Norwegian Institute of Public Health · NOOslo University Hospital · NOKing's College London · GBNorwegian University of Science and Technology · NOUniversity College London · GBUniversity College of Osteopathy · GBUniversity of Bristol · GB

Funding

Medical Research Council MC_UU_00011/1Medical Research Council MC_UU_00032/1MRF_ MRF-160-0002-ELP-PINGAWellcome TrustWellcome Trust 224092/Z/21/Z
6 · The paper itself

Abstract

Identifying mechanisms underlying the intergenerational transmission of risk for attention-deficit/hyperactivity disorder (ADHD) traits can inform interventions and provide insights into the role of parents in shaping their children's outcomes. We investigated whether genetic transmission and genetic nurture (environmentally mediated effects) underlie associations between polygenic scores indexing parental risk and protective factors and their offspring's ADHD traits. This birth cohort study included 19,506 genotyped mother-father-offspring trios from the Norwegian Mother, Father and Child Cohort Study. Polygenic scores were calculated for parental factors previously associated with ADHD, including psychopathology, substance use, neuroticism, educational attainment, and cognitive performance. Mothers reported on their 8-year-old children's ADHD traits (n = 9,454 children) using the Parent/Teacher Rating Scale for Disruptive Behaviour Disorders. We found that associations between ADHD maternal and paternal polygenic scores and child ADHD traits decreased significantly when adjusting for the child polygenic score (p

Indexed as

Attention Deficit Disorder with HyperactivityChildCohort StudiesFemaleGenotypeHumansMothersPhenotype

Identifiers

PMID36385167
PMCPMC10208953
OpenAlexW4309412887

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.