Evidence map›Paper›PMID 36385151›Full record

ArticleScientific reports2022

Investigating subtle changes in facial expression to assess acute pain in Japanese macaques.

Vanessa N Gris, Nelson Broche, Akihisa Kaneko, Munehiro Okamoto, Juri Suzuki, Daniel S Mills, Takako Miyabe-Nishiwaki

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Vanessa N GrisPrimate Research Institute, Kyoto University, Inuyama, Japan.
Nelson BrochePrimate Research Institute, Kyoto University, Inuyama, Japan.
Akihisa KanekoPrimate Research Institute, Kyoto University, Inuyama, Japan.
Munehiro OkamotoPrimate Research Institute, Kyoto University, Inuyama, Japan.
Juri SuzukiPrimate Research Institute, Kyoto University, Inuyama, Japan.
Daniel S MillsDepartment of Life Sciences, University of Lincoln, Lincoln, UK.
Takako Miyabe-NishiwakiPrimate Research Institute, Kyoto University, Inuyama, Japan. miyabe.takako.2s@kyoto-u.ac.jp.
Kyoto University · JPUniversity of Lincoln · GB

Funding

Japan Society for the Promotion of Science JP15K14364Japan Society for the Promotion of Science S19099Ministry of Education, Culture, Sports, Science and Technology 180464
6 · The paper itself

Abstract

Changes in facial expression provide cues for assessing emotional states in mammals and may provide non-verbal signals of pain. This study uses geometric morphometrics (GMM) to explore the facial shape variation in female Japanese macaques who underwent experimental laparotomy. Face image samples were collected from video footage of fourteen macaques before surgery and 1, 3, and 7 days after the procedure. Image samples in the pre-surgical condition were considered pain-free, and facial expressions emerging after surgery were investigated as potential indicators of pain. Landmarks for shape analysis were selected based on the underlying facial musculature and their corresponding facial action units and then annotated in 324 pre-surgical and 750 post-surgical images. The expression of pain is likely to vary between individuals. Tightly closed eyelids or squeezed eyes and lip tension were the most commonly observed facial changes on day 1 after surgery (p < 0.01974). A good overall inter-rater reliability [ICC = 0.99 (95% CI 0.75-1.0)] was observed with the method. The study emphasizes the importance of individualized assessment and provides a better understanding of facial cues to pain for captive macaque care.

Indexed as

Acute PainFacial ExpressionAnimalsFemaleMacacaMacaca fuscataMammalsReproducibility of Results

Identifiers

PMID36385151
PMCPMC9669003
OpenAlexW4309469404

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.