SynthesisScientific reports2022
Outcome of pulpotomy in permanent teeth with irreversible pulpitis: a systematic review and meta-analysis.
Synthesis in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 6 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Association of Apical Maturity With Clinical and Biological Outcomes After Regenerative Endodontic Procedures: A Systematic Review and Meta-Analysis.International dental journal · 2026Pooled it
- Clinical and radiographic outcomes of pulpotomy materials in permanent teeth: a systematic review of calcium hydroxide, MTA, biodentine, and iRoot BP plus.BMC oral health · 2025Pooled it
- Effectiveness of calcium hydroxide compared to hydraulic calcium silicate cements for direct pulp capping in managing deep caries in vital permanent teeth: A systematic review and meta-analysis.International endodontic journal · 2025Pooled it
- Pooled it
- Lasers efficacy in pain management after primary and secondary endodontic treatment: a systematic review and meta-analysis of randomized clinical trials.Scientific reports · 2024Pooled it
- Pooled it
- Postoperative pain after pulpotomy versus pulpectomy of primary molars with symptomatic irreversible pulpitis: an equivalent randomized clinical trial.BMC oral health · 2026Trial
- Assessing the Success of a Mineral Trioxide Aggregate and a Pre-Mixed Bioceramic in Mature Teeth With Irreversible Pulpitis With Full Pulpotomy: A Randomized Clinical Trial.Clinical and experimental dental research · 2025Trial
- Randomized clinical trial of pulpotomy using a premixed injectable calcium silicate cement on mature permanent teeth with reversible pulpitis.Scientific reports · 2024Trial
- A Conservative Restorative Protocol for Symptomatic Irreversible Pulpitis: Clinical Success and Rapid Pain Relief in a 27-Case Series with 36-Month Follow-Up.Dentistry journal · 2026Article
- Regenerative Endodontics in Teeth With Irreversible Pulpitis: A Scoping Review.International endodontic journal · 2026Article
- Establishment of an MRI-Based Diagnostic Approach to Identify Critical Pulpal Inflammation Zones in a Rat Caries-Derived Pulpitis Model.International endodontic journal · 2026Article
- Nonsurgical Endodontic Management of an Odontogenic Cutaneous Sinus Tract in a Child: A Case Report.Children (Basel, Switzerland) · 2026Article
- Fracture Resistance of Mineral Trioxide Aggregate- and Biodentine-Pulpotomized teeth with Different Restorative Techniques: An in vitro Study.Journal of dentistry (Shiraz, Iran) · 2026Article
- Determinants of Definitive Full Pulpotomy Adoption in Symptomatic Irreversible Pulpitis: A Multivariable Analysis of Dental Trainee Decision-Making.Healthcare (Basel, Switzerland) · 2026Article
- Review
- The role of transient receptor potential ankyrin 1 in pyroptosis during pulpitis development.BMC oral health · 2026Article
- Clinical Challenges and Therapeutic Approaches in Managing Deep Carious Lesions Close to the Pulp in Permanent Teeth: A Narrative Review.International journal of dentistry · 2026Review
- Comparative evaluation of NeoPUTTY and mineral trioxide aggregate for full pulpotomy in mature permanent molars with irreversible pulpitis: a randomized clinical study.Biomaterial investigations in dentistry · 2026Article
- TheraCal LC versus Mineral Trioxide Aggregate for full pulpotomy in cariously exposed mature permanent molars with symptomatic irreversible pulpitis: a randomized clinical trial.Biomaterial investigations in dentistry · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Treatment planning is key to clinical success. Permanent teeth diagnosed with "irreversible pulpitis" have long been implied to have an irreversibly damaged dental pulp that is beyond repair and warranting root canal treatment. However, newer clinical approaches such as pulpotomy, a minimally invasive and biologically based procedure have re-emerged to manage teeth with pulpitis. The primary aim of the study was to conduct a meta-analysis to comprehensively estimate the overall success rate of pulpotomy in permanent teeth with irreversible pulpitis as a result of carious pulp exposure. The secondary aim of the study was to investigate the effect of predictors such as symptoms, root apex development (closed versus open), and type of pulp capping material on the success rate of pulpotomy. Articles were searched using PubMed, Scopus, CENTRAL, and Web of Science databases, until January 2021. Outcomes were calculated by pooling the success rates with a random effect model. Comparison between the different subgroups was conducted using the z statistic test for proportion with significance set at alpha = 0.05. A total of 1,116 records were retrieved and 11 studies were included in the quantitative analysis. The pooled success rate for pulpotomy in teeth with irreversible pulpitis was 86% [95% CI: 0.76-0.92; I
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.