Evidence map›Paper›PMID 36384704›Full record

ArticleTrials2022

A randomised controlled trial to compare clinical and cost-effectiveness of an online parent-led treatment for child anxiety problems with usual care in the context of COVID-19 delivered in Child and Adolescent Mental Health Services in the UK (Co-CAT): a study protocol for a randomised controlled trial.

Lucy Taylor, Sophie Giles, Sophie Howitt, Zoe Ryan, Emma Brooks, Lucy Radley, Abigail Thomson, Emily Whitaker, Fauzia Knight, Claire Hill and 7 more

Open access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Lucy TaylorDepartments of Experimental Psychology and Psychiatry, University of Oxford, Oxford, UK. lucy.taylor@psych.ox.ac.uk.
Sophie GilesDepartments of Experimental Psychology and Psychiatry, University of Oxford, Oxford, UK.
Sophie HowittDepartments of Experimental Psychology and Psychiatry, University of Oxford, Oxford, UK.
Zoe RyanDepartments of Experimental Psychology and Psychiatry, University of Oxford, Oxford, UK.
Emma BrooksDepartments of Experimental Psychology and Psychiatry, University of Oxford, Oxford, UK.
Lucy RadleyDepartments of Experimental Psychology and Psychiatry, University of Oxford, Oxford, UK.
Abigail ThomsonDepartments of Experimental Psychology and Psychiatry, University of Oxford, Oxford, UK.
Emily WhitakerDepartments of Experimental Psychology and Psychiatry, University of Oxford, Oxford, UK.
Fauzia KnightDepartments of Experimental Psychology and Psychiatry, University of Oxford, Oxford, UK.
Claire HillSchool of Psychology and Clinical Language Sciences, University of Reading, Reading, UK.
Mara ViolatoHealth Economics Research Centre, Nuffield Department of Population Health, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.
Polly WaiteDepartments of Experimental Psychology and Psychiatry, University of Oxford, Oxford, UK.
Vanessa RaymontDepartment of Psychiatry, University of Oxford, Oxford, UK.
Ly-Mee YuOxford Primary Care Clinical Trials Unit, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Victoria HarrisOxford Primary Care Clinical Trials Unit, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Nicola WilliamsOxford Primary Care Clinical Trials Unit, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Cathy CreswellDepartments of Experimental Psychology and Psychiatry, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0003-1889-0956
University of Oxford · GBUniversity of Reading · GB

Funding

Medical Research Council DHSC/UKRI COVID-19 Rapid Response InitiativeMedical Research Council MR/V028510/1National Institute for Health Research NIHR204435- PRP (ST-01-42) CAMHS
6 · The paper itself

Abstract

backgroundIn the context of COVID-19, NHS Child and Adolescent Mental Health Services (CAMHS) and other children's mental health services have faced major challenges in providing psychological treatments that (i) work when delivered remotely and (ii) can be delivered efficiently to manage increases in referrals as social distancing measures have been relaxed. Anxiety problems are a common reason for referral to CAMHS, children with pre-existing anxiety problems are particularly vulnerable in the context of COVID-19, and there were concerns about increases in childhood anxiety as schools reopened. The proposed research will evaluate the clinical and cost-effectiveness of a brief online parent-led cognitive behavioural treatment (CBT) delivered by the OSI (Online Support and Intervention for child anxiety) platform with remote support from a CAMHS therapist compared to 'COVID-19 treatment as usual' (C-TAU) in CAMHS and other children's mental health services throughout the COVID-19 pandemic.

methodsWe will conduct a two-arm, multi-site, randomised controlled non-inferiority trial to evaluate the clinical and cost-effectiveness of OSI with therapist support compared to CAMHS and other child mental health services 'COVID-19 treatment as usual' (C-TAU) during the COVID-19 outbreak and to explore parent and therapists' experiences. DISCUSSION: If non-inferiority is shown, the research will provide (1) a solution for efficient psychological treatment for child anxiety disorders while social distancing (for the COVID-19 context and future pandemics); (2) an efficient means of treatment delivery as 'normal service' resumes to enable CAMHS to cope with the anticipated increase in referrals; and (3) a demonstration of rapid, high-quality evaluation and application of online interventions within NHS CAMHS to drive forward much-needed further digital innovation and evaluation in CAMHS settings. The primary beneficiaries will be children with anxiety disorders and their families, NHS CAMHS teams, and commissioners who will access a potentially effective, cost-effective, and efficient treatment for child anxiety problems.

trial registrationISRCTN ISRCTN12890382 . Registered prospectively on 23 October 2020.

Indexed as

COVID-19Mental Health ServicesAnxietyAnxiety DisordersCost-Benefit AnalysisCOVID-19 Drug TreatmentEquivalence Trials as TopicHumansPandemicsParentsRandomized Controlled Trials as TopicUnited KingdomCAMHSCBTChild anxietyCOVID-19Digital healthInterventionParent-ledRandomised controlled trial

Identifiers

PMID36384704
PMCPMC9667839
OpenAlexW4309466084

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.