Evidence map›Paper›PMID 36384502›Full record

ArticleBMC nephrology2022

March hemoglobinuria progressed to acute kidney injury after kendo practice: a case report.

Maiko Yoshida, Hitoshi Suzuki, Sho Hamaguchi, Masako Iwasaki, Hiromitsu Fukuda, Hisatsugu Takahara, Shigeki Tomita, Yusuke Suzuki

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Maiko YoshidaDepartment of Nephrology, Juntendo University Urayasu Hospital, 2-1-1 Tomioka, Urayasu-Shi, Chiba, 279-0021, Japan.
Hitoshi SuzukiDepartment of Nephrology, Juntendo University Urayasu Hospital, 2-1-1 Tomioka, Urayasu-Shi, Chiba, 279-0021, Japan. shitoshi@juntendo.ac.jp.ORCID 0000-0002-1901-2111
Sho HamaguchiDepartment of Nephrology, Juntendo University Urayasu Hospital, 2-1-1 Tomioka, Urayasu-Shi, Chiba, 279-0021, Japan.
Masako IwasakiDepartment of Nephrology, Juntendo University Urayasu Hospital, 2-1-1 Tomioka, Urayasu-Shi, Chiba, 279-0021, Japan.
Hiromitsu FukudaDepartment of Nephrology, Juntendo University Urayasu Hospital, 2-1-1 Tomioka, Urayasu-Shi, Chiba, 279-0021, Japan.
Hisatsugu TakaharaDepartment of Nephrology, Juntendo University Urayasu Hospital, 2-1-1 Tomioka, Urayasu-Shi, Chiba, 279-0021, Japan.
Shigeki TomitaDepartment of Pathology, Juntendo University Urayasu Hospital, Chiba, Japan.
Yusuke SuzukiDepartment of Nephrology, Juntendo University Faculty of Medicine, Tokyo, Japan.
Juntendo University Urayasu Hospital · JPJuntendo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMarch hemoglobinuria is caused by a hemolytic mechanism due to transient hematuria after physical exercise which, although rare, may lead to acute kidney injury. We report a case of a patient with march hemoglobinuria induced by kendo, which was diagnosed by the presence of Berlin blue iron staining in the proximal tubules through renal biopsy. CASE PRESENTATION: A 15-year-old male complained of fever (37 °C), general malaise, and nausea after hard kendo sessions. Laboratory findings revealed indirect bilirubin dominant hyperbilirubinemia (total bilirubin 3.8 mg/dL), high lactate dehydrogenase (LDH), and acute kidney injury (serum creatinine: 3.11 mg/dL and estimated glomerular filtration rate: 26 mL/min/1.73m

conclusionsMarch hemoglobinuria is a hemolytic disease that can occur after intense exercise, especially kendo. Considering its rarity due to the lack of critical symptoms, it is important to note that occult blood-positive findings may be indicative of march hemoglobinuria if the patient underwent strenuous exercise. Therefore, clinicians should be aware of this possibility to provide timely and appropriate treatment.

Indexed as

Acute Kidney InjuryAnemia, HemolyticAdolescentBilirubinFerrocyanidesHematuriaHemoglobinuriaHemolysisHumansIronMaleBilirubinferric ferrocyanideFerrocyanidesIronAcute kidney injuryExertional hemoglobinuriaHemosiderin depositMarch hemoglobinuriaRenal biopsy

Identifiers

PMID36384502
PMCPMC9670421
OpenAlexW4309323704

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.