ArticleBMC geriatrics2022
Frailty and solid-organ transplant candidates: a scoping review.
Article in BMC geriatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Change in frailty status in the 12 months following solid organ transplantation: a systematic review and meta-analysis.Age and ageing · 2025Pooled it
- Should Adherence to Medical Recommendations Be a Requirement for Kidney Transplant Candidacy?The American journal of bioethics : AJOB · 2026Article
- The HE scale: a consensus-based, time-aware rapid recovery scale for lung transplantation.Journal of thoracic disease · 2026Article
- Article
- Frailty Screening and Prehabilitation Before Kidney Transplant Listing: A Practical Narrative Review.Cureus · 2026Review
- Optimizing patient outcomes in interstitial lung disease through pre- and post-transplant management strategies.World journal of transplantation · 2025Review
- Article
- The perioperative management of geriatric patients in transplantation surgery-clinical, immunological, and translational considerations.Frontiers in transplantation · 2025Review
- The Path Forward: A Review on Enhanced Recovery After Cardiothoracic Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2025Review
- Impact of Medicaid expansion on kidney transplantation in the State Oklahoma.World journal of transplantation · 2024Article
- Exploration of the causality of frailty index on psoriasis: A Mendelian randomization study.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024Article
- Comprehensive geriatric assessment predicts listing for kidney transplant in patients with end-stage renal disease: a retrospective cohort study.BMC geriatrics · 2024Article
- Putting Guidelines Into Practice: Is Frailty Measurement at the Time of Kidney Transplant Eligibility Assessment Valid, Feasible, and Acceptable to Patients?Transplantation direct · 2023Article
- Nutritional Risk of Candidates for Simultaneous Pancreatic-Kidney Transplantation-A Narrative Review.Nutrients · 2023Review
- Use of frailty assessment instruments in nephrology populations: a scoping review.BMC geriatrics · 2023Article
- From Listing to Recovery: A Review of Nutritional Status Assessment and Management in Liver Transplant Patients.Nutrients · 2023Review
- Anthropometrics, body composition, sarcopenia, and frailty in intestinal transplantation: A literature review and commentary.Intestinal Failure (New York, N.Y.)Review
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is currently no consensus as to a standardized tool for frailty measurement in any patient population. In the solid-organ transplantation population, routinely identifying and quantifying frailty in potential transplant candidates would support patients and the multidisciplinary team to make well-informed, individualized, management decisions. The aim of this scoping review was to synthesise the literature regarding frailty measurement in solid-organ transplant (SOT) candidates.
methodsA search of four databases (Cochrane, Pubmed, EMBASE and CINAHL) yielded 3124 studies. 101 studies (including heart, kidney, liver, and lung transplant candidate populations) met the inclusion criteria.
resultsWe found that studies used a wide range of frailty tools (N = 22), including four 'established' frailty tools. The most commonly used tools were the Fried Frailty Phenotype and the Liver Frailty Index. Frailty prevalence estimates for this middle-aged, predominantly male, population varied between 2.7% and 100%. In the SOT candidate population, frailty was found to be associated with a range of adverse outcomes, with most evidence for increased mortality (including post-transplant and wait-list mortality), post-operative complications and prolonged hospitalisation. There is currently insufficient data to compare the predictive validity of frailty tools in the SOT population.
conclusionOverall, there is great variability in the approach to frailty measurement in this population. Preferably, a validated frailty measurement tool would be incorporated into SOT eligibility assessments internationally with a view to facilitating comparisons between patient sub-groups and national and international transplant services with the ultimate goal of improved patient care.
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