ArticleBMC geriatrics2022
The relationship between physical activity trajectories and frailty: a 20-year prospective cohort among community-dwelling older people.
Article in BMC geriatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 17 citations in OpenAlex.
- Long-Term Physical Activity Patterns and Risk of Future Frailty: A Systematic Review and Age-Stratified Meta-Analysis.Geriatrics (Basel, Switzerland) · 2026Review
- Association between oral health and frailty among older cancer patients: a cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Impact of physical activity and frailty on mortality and utilization among middle-aged and older adults in South Korea.The Journal of frailty & aging · 2026Article
- Frailty and Physical Activity: A Compositional Isotemporal Substitution Analysis from the All of Us Research Program.Journal of frailty, sarcopenia and falls · 2025Article
- Associations between malnutrition and physical performance, sarcopenia, and frailty in older adults.BMC geriatrics · 2025Article
- Observational
- Causal associations between leisure sedentary behaviors and sleep status with frailty: insight from Mendelian randomization study.BMC geriatrics · 2024Article
- Integrating frailty interventions into existing care models: a comprehensive approach to enhancing patient outcomes in chronic disease management.Frontiers in public health · 2024Review
- Dietary inflammatory index and disability among older adults in Guangzhou: a cross-sectional analysis.Frontiers in public health · 2024Article
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Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStudies on examining the relationship between physical activity patterns and frailty are lacking. This study examined physical activity patterns in older people and investigated the relationship between physical activity and frailty as well as identifying the predictors of frailty.
methodsWe used a nationally representative longitudinal database, the Taiwan Longitudinal Study of Aging (TLSA) database, and data for a 20-year period were extracted and analyzed. A total of 5131 participants aged ≥ 60 years in 1996 were included in the current analysis. Information regarding demographic characteristics, frailty, physical activity, comorbidities, oral health, and depressive symptoms was extracted from the TLSA database. Physical activity patterns were examined using group-based trajectory modeling from 1996 to 2015. Potential predictors were examined by performing multivariate logistic regression.
resultsFour trajectories of the physical activity pattern were found: consistently physically inactive (33.7%), consistently physically active (21.5%), incline (21.6%), and decline (23.2%). Throughout the period, the trajectories of the four groups significantly differed from each other at year 2015, with the incline and decline groups exhibiting the lowest and highest frailty scores, respectively (p < 0.001). Older age, male, poor oral health, diabetes, chronic kidney disease, and depressive symptoms were identified as risk factors for frailty.
conclusionPhysical activity reduces the risk of chronic conditions, which contributes to healthy longevity. This study can guide the development of future research and interventions to manage frailty in older people, particularly in considering previous physical activity trajectories within the life course.
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