Evidence map›Paper›PMID 36383501›Full record

ArticleASN neuro

Translocation of High Mobility Group Box 1 From the Nucleus to the Cytoplasm in Depressed Patients With Epilepsy.

Xiao-Li Li, Shu Wang, Chong-Yang Tang, Hao-Wei Ma, Zi-Zhang Cheng, Meng Zhao, Wei-Jin Sun, Xiong-Fei Wang, Meng-Yang Wang, Tian-Fu Li and 4 more

Open access · goldAbstract read
In one paragraph

Article in ASN neuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Apigenin Regulating PI3K/AKT Pathway to Improve Depressive Behavior in Epileptic Rats.Combinatorial chemistry & high throughput screening · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Xiao-Li LiDepartment of Neurology, Affiliated ZhongDa Hospital, Southeast University, Nanjing, China.
Shu WangDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Chong-Yang TangDepartment of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing, China.
Hao-Wei MaDepartment of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing, China.
Zi-Zhang ChengDepartment of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing, China.
Meng ZhaoDepartment of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing, China.
Wei-Jin SunDepartment of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing, China.
Xiong-Fei WangDepartment of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing, China.
Meng-Yang WangDepartment of Neurology, Sanbo Brain Hospital, Capital Medical University, Beijing, China.
Tian-Fu LiDepartment of Neurology, Sanbo Brain Hospital, Capital Medical University, Beijing, China.
Xue-Ling QiDepartment of Pathology, Sanbo Brain Hospital, Capital Medical University, Beijing, China.
Jian ZhouDepartment of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing, China.
Guo-Ming LuanDepartment of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing, China.
Yu-Guang GuanDepartment of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing, China.ORCID 0000-0001-9945-2872
Capital Medical University · CNZhongda Hospital Southeast University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Depression is a common psychiatric comorbidity in patients with epilepsy, especially those with temporal lobe epilepsy (TLE). The aim of this study was to assess changes in high mobility group box protein 1 (HMGB1) expression in epileptic patients with and without comorbid depression. Sixty patients with drug-resistant TLE who underwent anterior temporal lobectomy were enrolled. Anterior hippocampal samples were collected after surgery and analyzed by immunofluorescence (

Indexed as

EpilepsyEpilepsy, Temporal LobeHMGB1 ProteinCytoplasmGliosisHippocampusHumansSclerosisHMGB1 Proteincomorbiditydepressionhigh mobility group box 1hippocampustemporal lobe epilepsy

Identifiers

PMID36383501
PMCPMC9677174
OpenAlexW4309655956

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.