Evidence map›Paper›PMID 36383497›Full record

ArticleMachine learning in medical imaging. MLMI (Workshop)2020

Temporal-Adaptive Graph Convolutional Network for Automated Identification of Major Depressive Disorder Using Resting-State fMRI.

Dongren Yao, Jing Sui, Erkun Yang, Pew-Thian Yap, Dinggang Shen, Mingxia Liu

Open access · greenAbstract read
In one paragraph

Article in Machine learning in medical imaging. MLMI (Workshop), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
13.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Dongren YaoBrainentome Center and National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, China.
Jing SuiBrainentome Center and National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, China.
Erkun YangDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Pew-Thian YapDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Dinggang ShenDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Mingxia LiuDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
University of North Carolina at Chapel Hill · USChinese Academy of Sciences · CNInstitute of Automation · CN

Funding

Quantifying Brain Abnormality by Multimodality Neuroimage Analysis,R01AG041721 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LIU, MINGXIA · 2012 to 2019
$3.0M
2/2 Phenotype Predictors of Cognitive Outcomes in Geriatric DepressionR01MH108560 · NIMH · DUKE UNIVERSITY · PI POTTER, GUY GLENN · 2016 to 2020
$1.8M
NIA NIH HHS R01 AG041721NIMH NIH HHS R01 MH108560
6 · The paper itself

Abstract

Extensive studies focus on analyzing human brain functional connectivity from a network perspective, in which each network contains complex graph structures. Based on resting-state functional MRI (rs-fMRI) data, graph convolutional networks (GCNs) enable comprehensive mapping of brain functional connectivity (FC) patterns to depict brain activities. However, existing studies usually characterize static properties of the FC patterns, ignoring the time-varying dynamic information. In addition, previous GCN methods generally use fixed group-level (e.g., patients or controls) representation of FC networks, and thus, cannot capture subject-level FC specificity. To this end, we propose a Temporal-Adaptive GCN (TAGCN) framework that can not only take advantage of both spatial and temporal information using resting-state FC patterns and time-series but also explicitly characterize subject-level specificity of FC patterns. Specifically, we first segment each ROI-based time-series into multiple overlapping windows, then employ an adaptive GCN to mine topological information. We further model the temporal patterns for each ROI along time to learn the periodic brain status changes. Experimental results on 533 major depressive disorder (MDD) and health control (HC) subjects demonstrate that the proposed TAGCN outperforms several state-of-the-art methods in MDD vs. HC classification, and also can be used to capture dynamic FC alterations and learn valid graph representations.

Identifiers

PMID36383497
PMCPMC9645786
OpenAlexW3091005297

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.