Evidence map›Paper›PMID 36383019›Full record

ArticleApplied and environmental microbiology2022

Global Cellular Metabolic Rewiring Adapts Corynebacterium glutamicum to Efficient Nonnatural Xylose Utilization.

Xi Sun, Yufeng Mao, Jiahao Luo, Pi Liu, Meiru Jiang, Guimei He, Zhidan Zhang, Qichen Cao, Jie Shen, Hongwu Ma and 2 more

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Engineering riboflavin-overproducingSynthetic and systems biotechnology · 2026
    Article
  2. Article
  3. Single Mutation inMicroorganisms · 2025
    Article
  4. Article
  5. EngineeringBiodesign research · 2025
    Review
  6. EngineeringSynthetic and systems biotechnology · 2024
    Article
  7. Multi-modular metabolic engineering of heme synthesis inSynthetic and systems biotechnology · 2024
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xi Sun *Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin Universitygrid.33763.32, Tianjin, China.
Yufeng Mao *Biodesign Center, Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnologygrid.458513.e, Chinese Academy of Sciences, Tianjin, China.
Jiahao LuoKey Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin Universitygrid.33763.32, Tianjin, China.
Pi LiuBiodesign Center, Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnologygrid.458513.e, Chinese Academy of Sciences, Tianjin, China.
Meiru JiangKey Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin Universitygrid.33763.32, Tianjin, China.
Guimei HeKey Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin Universitygrid.33763.32, Tianjin, China.
Zhidan ZhangBiodesign Center, Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnologygrid.458513.e, Chinese Academy of Sciences, Tianjin, China.
Qichen CaoBiodesign Center, Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnologygrid.458513.e, Chinese Academy of Sciences, Tianjin, China.
Jie ShenBiodesign Center, Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnologygrid.458513.e, Chinese Academy of Sciences, Tianjin, China.
Hongwu MaBiodesign Center, Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnologygrid.458513.e, Chinese Academy of Sciences, Tianjin, China.
Tao ChenKey Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin Universitygrid.33763.32, Tianjin, China.
Zhiwen WangKey Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin Universitygrid.33763.32, Tianjin, China.ORCID 0000-0001-8938-3631

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Xylose, the major component of lignocellulosic biomass, cannot be naturally or efficiently utilized by most microorganisms. Xylose (co)utilization is considered a cornerstone of efficient lignocellulose-based biomanufacturing. We evolved a rapidly xylose-utilizing strain, Cev2-18-5, which showed the highest reported specific growth rate (0.357 h

Indexed as

Corynebacterium glutamicumCarbonGlucoseMetabolic EngineeringSuccinatesTranscription FactorsXyloseCarbonGlucoseSuccinatesTranscription FactorsXylosecarbon catabolite repressionCorynebacterium glutamicumlignocellulosic biorefinerysynergistic effectxylose

Identifiers

PMID36383019
PMCPMC9746319

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.