Evidence map›Paper›PMID 36382946›Full record

ReviewJournal of the American Heart Association2022

Genetics of BAG3: A Paradigm for Developing Precision Therapies for Dilated Cardiomyopathies.

Hui-Qi Qu, Arthur M Feldman, Hakon Hakonarson

Open access · goldAbstract readReview
In one paragraph

Review in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. RNA-Based Therapies for Treating Monogenic Cardiomyopathies.The Canadian journal of cardiology · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Frontiers in genetics · 2025
    Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Hui-Qi QuThe Center for Applied Genomics, Children's Hospital of Philadelphia Philadelphia PA.ORCID 0000-0001-9317-4488
Arthur M FeldmanDepartment of Medicine, Division of Cardiology The Lewis Katz School of Medicine at Temple University Philadelphia PA.
Hakon HakonarsonThe Center for Applied Genomics, Children's Hospital of Philadelphia Philadelphia PA.ORCID 0000-0003-2814-7461
Children's Hospital of Philadelphia · USTemple University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nonischemic dilated cardiomyopathy is a common form of heart muscle disease in which genetic factors play a critical etiological role. In this regard, both rare disease-causing mutations and common disease-susceptible variants, in the Bcl-2-associated athanogene 3 (

Indexed as

Cardiomyopathy, DilatedAdaptor Proteins, Signal TransducingApoptosis Regulatory ProteinsHumansAdaptor Proteins, Signal TransducingApoptosis Regulatory ProteinsBAG3 protein, humanBAG3dilated cardiomyopathygeneticsheart failureINPP5Fprecision medicine

Identifiers

PMID36382946
PMCPMC9851466
OpenAlexW4309151439

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.