Evidence map›Paper›PMID 36382775›Full record

ReviewThe neuroradiology journal2024

Skull base infections, their complications, and management.

Phat Tan Nguyen, Jennifer Chang, Kiarash Shahlaie, Osama Raslan, Arzu Ozturk, Matthew Bobinski, Reza Assadsangabi

Open access · greenAbstract readReview
In one paragraph

Review in The neuroradiology journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Phat Tan NguyenInternal Medicine, Kaiser Permanente San Francisco, San Francisco, CA, USA.ORCID 0000-0001-6014-7483
Jennifer ChangDepartment of Radiology, University of California Davis School of Medicine, Sacramento, CA, USA.
Kiarash ShahlaieDepartment of Neurological Surgery, University of California Davis School of Medicine, Sacramento, CA, USA.
Osama RaslanDepartment of Radiology, University of California Davis School of Medicine, Sacramento, CA, USA.
Arzu OzturkDepartment of Radiology, University of California Davis School of Medicine, Sacramento, CA, USA.
Matthew BobinskiInternal Medicine, Kaiser Permanente San Francisco, San Francisco, CA, USA.
Reza AssadsangabiDepartment of Radiology, Keck School of Medicine of USC University of Southern California, Sacramento, CA, USA.
University of California, Davis · USKaiser Permanente San Francisco Medical Center · USNeurological Surgery · USUniversity of Southern California · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveOur review aims to summarize the current literature on skull base infections (SBIs) and retrospectively analyze any such cases encountered at our institution.

designA literature search was conducted using online databases PubMed, MEDLINE, and ResearchGate with the terms "skull base osteomyelitis," "temporal bone osteomyelitis," "skull base infections," "necrotizing otitis media," and "SBO". References from the resulting manuscripts were reviewed for relevant articles. A search of our electronic health records using the same key terms was also performed to identify patients with a tissue biopsy-confirmed diagnosis of skull base infections. Patients with an indeterminate diagnosis or inaccessible/poor imaging were excluded.

settingA level one trauma and major tertiary academic medical center.

participantsAll patients treated at the University of California Davis Health System with a confirmed diagnosis of skull base infections from January 2005 to November 2020.

main outcome measuresImaging results, symptoms, treatment, morbidity, and mortality.

resultsOur literature search yielded 59 articles ranging from 1982 to 2021. A retrospective search of our electronic health records identified two cases of skull base infections.

conclusionSkull base infections have no pathognomonic findings. A multimodal approach with computed tomography (CT), magnetic resonance imaging (MRI), and nuclear medicine is necessary to characterize the disease process in addition to a biopsy for definitive diagnosis. Other diagnoses can mimic SBI on imaging, such as nasopharyngeal carcinoma and inflammatory pseudotumor. Culture-guided antimicrobial treatment and surgery are mainstay therapies. Other adjuvant strategies currently lack the robust evidence necessary to characterize their risks and benefits.

Indexed as

OsteomyelitisSkull BaseBiopsyHumansMagnetic Resonance ImagingRetrospective StudiesTomography, X-Ray Computedinfectionmalignantmimicsnecrotizing otitis mediaosteomyelitisSkull base

Identifiers

PMID36382775
PMCPMC10863568
OpenAlexW4309157459

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.