Evidence map›Paper›PMID 36382687›Full record

ArticleTransboundary and emerging diseases2022

Co-circulation of alpha- and beta-coronaviruses in Pteropus vampyrus flying foxes from Indonesia.

Lena Ch'ng, Susan M Tsang, Zoe A Ong, Dolyce H W Low, Sigit Wiantoro, Ina L Smith, Nancy B Simmons, Yvonne C F Su, David J Lohman, Gavin J D Smith and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Transboundary and emerging diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 5 countries.

Lena Ch'ngProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore.ORCID https://orcid.org/0000-0002-3593-6584
Susan M TsangDepartment of Mammalogy, Division of Vertebrate Zoology, American Museum of Natural History, New York, New York, USA.ORCID https://orcid.org/0000-0002-7916-2074
Zoe A OngProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore.
Dolyce H W LowProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore.ORCID https://orcid.org/0000-0003-4399-7325
Sigit WiantoroMuseum Zoologicum Bogoriense, Research Center for Biosystematics and Evolution, National Research and Innovation Agency, Cibinong, West Java, Indonesia.ORCID https://orcid.org/0000-0001-6169-5772
Ina L SmithHealth and Biosecurity, The Commonwealth Scientific and Industrial Research Organization, Canberra, Australia.ORCID https://orcid.org/0000-0001-5807-3737
Nancy B SimmonsDepartment of Mammalogy, Division of Vertebrate Zoology, American Museum of Natural History, New York, New York, USA.ORCID https://orcid.org/0000-0001-8807-7499
Yvonne C F SuProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore.ORCID https://orcid.org/0000-0003-4349-9211
David J LohmanBiology Department, City College of New York, City University of New York, New York, New York, USA.ORCID https://orcid.org/0000-0002-0689-2906
Gavin J D SmithProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore.ORCID https://orcid.org/0000-0001-5031-468X
Ian H MendenhallProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore.ORCID https://orcid.org/0000-0003-4250-6459
Duke-NUS Medical School · SGThe Graduate Center, CUNY · USAmerican Museum of Natural History · USDuke University · USHealth Sciences and Nutrition · AUIndonesian Institute of Sciences · IDSingHealth Duke-NUS Academic Medical Centre · SG

Funding

Diversity and dispersal routes of bat-borne paramyxoviruses in densely populatedR21AI105050 · NIAID · CITY COLLEGE OF NEW YORK · PI LOHMAN, DAVID J. · 2013 to 2014
$353k
American Philosophical SocietyNational Geographic Young Explorers Grant 9272-13NIAID NIH HHS R21 AI105050NIH HHS R21 AI105050-01The Ministry of Health, Singapore
6 · The paper itself

Abstract

Bats are important reservoirs for alpha- and beta-coronaviruses. Coronaviruses (CoV) have been detected in pteropodid bats from several Southeast Asian countries, but little is known about coronaviruses in the Indonesian archipelago in proportion to its mammalian biodiversity. In this study, we screened pooled faecal samples from the Indonesian colonies of Pteropus vampyrus with unbiased next-generation sequencing. Bat CoVs related to Rousettus leschenaultii CoV HKU9 and Eidolon helvum CoV were detected. The 121 faecal samples were further screened using a conventional hemi-nested pan-coronavirus PCR assay. Three positive samples were successfully sequenced, and phylogenetic reconstruction revealed the presence of alpha- and beta-coronaviruses. CoVs belonging to the subgenera Nobecovirus, Decacovirus and Pedacovirus were detected in a single P. vampyrus roost. This study expands current knowledge of coronavirus diversity in Indonesian flying foxes, highlighting the need for longitudinal surveillance of colonies as continuing urbanization and deforestation heighten the risk of spillover events.

Indexed as

ChiropteraCoronavirusCoronavirus InfectionsAnimalsIndonesiaPhylogenyChiropteraphylogenyspilloverzoonotic

Identifiers

PMID36382687
PMCPMC9898127
OpenAlexW4309162328

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.