Evidence map›Paper›PMID 36382588›Full record

ReviewJournal of paediatrics and child health2022

Thyroid nodules in children and adolescents: Investigation and management.

Jessica L Sandy, Angela Titmuss, Shihab Hameed, Yoon Hi Cho, Gideon Sandler, Paul Benitez-Aguirre

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of paediatrics and child health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Predictors of thyroid cancer in paediatric patients with thyroid nodules: A systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Pooled it
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  6. Thyroid cancer: experience at a state pediatric referral center.Revista da Associacao Medica Brasileira (1992) · 2026
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  11. Who Is Diagnosing Pediatric Thyroid Nodules? A Tertiary Children's Hospital Review.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025
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  15. Association between long-term exposure to PMEnvironmental health : a global access science source · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jessica L SandyInstitute of Endocrinology and Diabetes, The Children's Hospital at Westmead, Westmead, New South Wales, Australia.
Angela TitmussDivision of Women, Children and Youth, Royal Darwin Hospital, Darwin, Australia.
Shihab HameedChild & Adolescent Health, Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.
Yoon Hi ChoInstitute of Endocrinology and Diabetes, The Children's Hospital at Westmead, Westmead, New South Wales, Australia.ORCID 0000-0001-6568-8991
Gideon SandlerDepartment of Surgery, The Children's Hospital at Westmead, Westmead, New South Wales, Australia.
Paul Benitez-AguirreInstitute of Endocrinology and Diabetes, The Children's Hospital at Westmead, Westmead, New South Wales, Australia.ORCID 0000-0002-7687-2898
The University of Sydney · AUCharles Darwin University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinically detectable thyroid nodules are less common in children than adults. However, they are associated with an increased risk of malignancy. Therefore, thorough evaluation of paediatric thyroid nodules is necessary, and an understanding of the features associated with a higher risk of malignancy is important to guide management and referral. Thyroid cancer in children differs significantly from that seen in adults in terms of genetics, presentation, response to treatment and prognosis. Children often present with more advanced disease, but the vast majority have excellent long-term prognosis. Evaluation and management of thyroid nodules and thyroid cancer require a multidisciplinary team approach and involvement of specialists with experience in this field. This review summarises investigative pathways for thyroid nodules in children and outlines current management strategies for paediatric thyroid nodules and cancer.

Indexed as

Thyroid NeoplasmsThyroid NoduleAdolescentAdultChildHumansPrognosisRetrospective StudiesThyroidectomypaediatricsthyroid cancerthyroidectomythyroid nodules

Identifiers

PMID36382588
PMCPMC10099987
OpenAlexW4309119143

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.