Evidence map›Paper›PMID 36382356›Full record

ArticleHepatology communications2022

Promotion of diet-induced obesity and metabolic syndromes by BID is associated with gut microbiota.

Shengmin Yan, Jun Zhou, Hao Zhang, Zhen Lin, Bilon Khambu, Gang Liu, Michelle Ma, Xiaoyun Chen, Naga Chalasani, Xiao-Ming Yin

Open access · goldAbstract read
In one paragraph

Article in Hepatology communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Hypolipidemic Effects ofPharmaceuticals (Basel, Switzerland) · 2025
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 3 countries.

Shengmin YanDepartment of Pathology and Laboratory Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA.ORCID 0000-0003-4012-9557
Jun ZhouDepartment of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Hao ZhangDepartment of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Zhen LinDepartment of Pathology and Laboratory Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Bilon KhambuDepartment of Pathology and Laboratory Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA.ORCID 0000-0002-9432-2064
Gang LiuDepartment of Pathology and Laboratory Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Michelle MaDepartment of Pathology and Laboratory Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Xiaoyun ChenDepartment of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Naga ChalasaniDepartment of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Xiao-Ming YinDepartment of Pathology and Laboratory Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA.ORCID 0000-0002-8576-6093
Tulane University · USCentral South University · CN

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI AUGUSTO C. OCHOA · 2012 to 2026
$69.1M
Translation CoreP30DK097512 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI Carmella Evans-Molina · 2015 to 2026
$17.4M
The Role of HMGB1 in autophagy deficiency-induced liver pathologyR01DK116605 · NIDDK · TULANE UNIVERSITY OF LOUISIANA · PI YIN, XIAO-MING · 2018 to 2021
$1.7M
NIDDK NIH HHS P30 DK097512NIDDK NIH HHS R01 DK116605NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

A growing body of evidence has indicated an expanding functional network of B-cell lymphoma 2 (BCL-2) family proteins beyond regulation of cell death and survival. Here, we examined the role and mechanisms of BH3 interacting-domain death agonist (BID), a pro-death BCL-2 family member, in the development of diet-induced metabolic dysfunction. Mice deficient in bid (bid

Indexed as

Gastrointestinal MicrobiomeMetabolic SyndromeAnimalsBH3 Interacting Domain Death Agonist ProteinDiet, High-FatMiceObesityProto-Oncogene Proteins c-bcl-2BH3 Interacting Domain Death Agonist ProteinBid protein, mouseProto-Oncogene Proteins c-bcl-2

Identifiers

PMID36382356
PMCPMC9701492
OpenAlexW4309164440

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.