Evidence map›Paper›PMID 36382184›Full record

ReviewComputational and structural biotechnology journal2022

Multiscale modelling of claudin-based assemblies: A magnifying glass for novel structures of biological interfaces.

Alessandro Berselli, Fabio Benfenati, Luca Maragliano, Giulio Alberini

Abstract readReview
In one paragraph

Review in Computational and structural biotechnology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Ion and water permeation through claudin-10b and claudin-15 paracellular channels.Computational and structural biotechnology journal · 2024
    Article
  9. Review
  10. A short guide to the tight junction.Journal of cell science · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alessandro BerselliCenter for Synaptic Neuroscience and Technology (NSYN@UniGe), Istituto Italiano di Tecnologia, Largo Rosanna Benzi, 10, 16132 Genova, Italy.
Fabio BenfenatiCenter for Synaptic Neuroscience and Technology (NSYN@UniGe), Istituto Italiano di Tecnologia, Largo Rosanna Benzi, 10, 16132 Genova, Italy.
Luca MaraglianoCenter for Synaptic Neuroscience and Technology (NSYN@UniGe), Istituto Italiano di Tecnologia, Largo Rosanna Benzi, 10, 16132 Genova, Italy.
Giulio AlberiniCenter for Synaptic Neuroscience and Technology (NSYN@UniGe), Istituto Italiano di Tecnologia, Largo Rosanna Benzi, 10, 16132 Genova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Claudins (Cldns) define a family of transmembrane proteins that are the major determinants of the tight junction integrity and tissue selectivity. They promote the formation of either barriers or ion-selective channels at the interface between two facing cells, across the paracellular space. Multiple Cldn subunits form complexes that include

Indexed as

APBS, adaptive Poisson-Boltzmann solverBBB, blood-brain barrierCAPRI, critical assessment of prediction of interactionscCPE, C-terminal fragment of the Clostridium perfringens enterotoxinCG, coarse grainedClaudinCLDN, claudinCNS, central nervous systemCoarse grained molecular dynamics simulationsCV, collective variableEA+, ethyl ammoniumECH, extracellular helixECL, extracellular loopFE, free energyFFEM, freeze-fracture electron microscopyFree energy calculationsFRET, fluorescence resonance energy transferGPU, graphics processing unitHB, hydrogen bondsICL, intracellular loopMA+, methylammoniumMDCK, Madin-Darby canine kidneyMD, molecular dynamicsMFPT, mean first passage timeMolecular dynamics simulationsNMR, nuclear magnetic resonancePAGE, polyacrylamide gel electrophoresisPANEL, protein association energy landscapePDB, protein data bankPMF, potential of mean forceProtein-protein molecular dockingSF, selectivity filterSTED, super-resolution stimulated emission microscopyTEA+, tetraethylammoniumTEER, transepithelial electric resistanceTEM, transmission electron microscopyTight junctionsTJ, tight junctionTMA+, tetramethylammoniumUS, umbrella samplingWT, wild typeX-RD, X-ray diffraction

Identifiers

PMID36382184
PMCPMC9647347

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.