Evidence map›Paper›PMID 36382178›Full record

ArticleComputational and structural biotechnology journal2022

Integrated gut microbiome and metabolome analyses identified fecal biomarkers for bowel movement regulation by

Yuya Nakamura, Shinya Suzuki, Shinnosuke Murakami, Yuichiro Nishimoto, Koichi Higashi, Naoki Watarai, Junpei Umetsu, Chiharu Ishii, Yutaro Ito, Yuka Mori and 3 more

Open access · goldAbstract read
In one paragraph

Article in Computational and structural biotechnology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Review
  7. Article
  8. Article
  9. The Nutritional Efficacy ofFrontiers in nutrition · 2021
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Yuya NakamuraMetagen Inc., 246-2 Kakuganji, Tsuruoka, Yamagata 997-0052, Japan.
Shinya SuzukiDepartment of Life Science and Technology, Tokyo Institute of Technology, 2-12-1 Ookayama, Meguro-ku, Tokyo 152-8550, Japan.
Shinnosuke MurakamiMetagen Inc., 246-2 Kakuganji, Tsuruoka, Yamagata 997-0052, Japan.
Yuichiro NishimotoMetagen Inc., 246-2 Kakuganji, Tsuruoka, Yamagata 997-0052, Japan.
Koichi HigashiNational Institute of Genetics, Genome Evolution Laboratory, Yata 1111, Mishima 411-8540, Japan.
Naoki WataraiDepartment of Life Science and Technology, Tokyo Institute of Technology, 2-12-1 Ookayama, Meguro-ku, Tokyo 152-8550, Japan.
Junpei UmetsuDepartment of Life Science and Technology, Tokyo Institute of Technology, 2-12-1 Ookayama, Meguro-ku, Tokyo 152-8550, Japan.
Chiharu IshiiInstitute for Advanced Biosciences, Keio University, 246-2 Kakuganji, Tsuruoka, Yamagata 997-0052, Japan.
Yutaro ItoInstitute for Advanced Biosciences, Keio University, 246-2 Kakuganji, Tsuruoka, Yamagata 997-0052, Japan.
Yuka MoriMetagen Inc., 246-2 Kakuganji, Tsuruoka, Yamagata 997-0052, Japan.
Mamiko KohnoMORISHITA JINTAN CO., LTD, Health Care Product Department, Research & Development Division, 1-2-40 Tamatsukuri, Chuo-ku, Osaka 540-8566, Japan.
Takuji YamadaMetagen Inc., 246-2 Kakuganji, Tsuruoka, Yamagata 997-0052, Japan.
Shinji FukudaMetagen Inc., 246-2 Kakuganji, Tsuruoka, Yamagata 997-0052, Japan.
Tokyo Institute of Technology · JPKeio University · JPMorishita Jintan (Japan) · JPNational Institute of Genetics · JPUniversity of Tsukuba · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Results: A randomized, double-blind controlled crossover trial was conducted with 24 adults who mainly tended to be constipated. The subjects received a two-week dietary intervention consisting of Conclusions: Intestinal microbiome and metabolome profiles might be utilized as potential markers of improved bowel movement after

Indexed as

16S rRNA gene sequenceAUROC, area under the receiver operating characteristic curveBifidobacteriaCE-TOFMS, capillary electrophoresis time-of-flight mass spectrometryCSA, D-camphor-10-sulfonic acidESVs, exact sequence variantsFDR, false discovery rateGut microbiotaIBD, inflammatory bowel diseaseIBS, irritable bowel syndromeITT, intention-to-treatMachine learningMCMC, Markov Chain Monte CarloMDS, multidimensional scalingMetabologenomicsNRs, nonrespondersPP, per-protocol populationProbioticsPSRF, potential scale reduction factorSCFAs, short-chain fatty acidsSRs, strong respondersWAIC, Widely Applicable Information CriterionWRs, weak responders

Identifiers

PMID36382178
PMCPMC9636538
OpenAlexW4307646554

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.