Evidence map›Paper›PMID 36382155›Full record

ArticleGlobal heart2022

Ideal Cardiovascular Health: Distribution, Determinants and Relationship with Health Status among People Living with HIV in Urban Tanzania.

Theresia A Ottaru, Gideon P Kwesigabo, Zeeshan Butt, Adovich S Rivera, Pilly Chillo, Helen Siril, Lisa R Hirschhorn, Matthew J Feinstein, Claudia Hawkins

Open access · goldAbstract read
In one paragraph

Article in Global heart, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
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  5. ComparingAIDS care · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Theresia A OttaruDepartment of Epidemiology and Biostatistics, Muhimbili University of Health and Allied Sciences, Dar Es Salaam, Tanzania.ORCID 0000-0002-1247-4938
Gideon P KwesigaboDepartment of Epidemiology and Biostatistics, Muhimbili University of Health and Allied Sciences, Dar Es Salaam, Tanzania.ORCID 0000-0003-3302-6736
Zeeshan ButtPhreesia, Inc, Delaware, US.ORCID 0000-0001-9739-3506
Adovich S RiveraInstitute for Public Health and Management, Feinberg School of Medicine, Northwestern University, Illinois, US.ORCID 0000-0003-2533-0818
Pilly ChilloDepartment of Internal Medicine, Muhimbili University of Health and Allied Sciences, Dar Es Salaam, Tanzania.ORCID 0000-0001-7073-1122
Helen SirilManagement and Development for Health, Dar es Salaam, Tanzania.ORCID 0000-0002-0628-3617
Lisa R HirschhornDepartment of Medical Social Sciences and Robert J Havey Institute of Global Health, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, US.ORCID 0000-0002-4355-7437
Matthew J FeinsteinDivision of Cardiology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Illinois, US.ORCID 0000-0002-8958-7666
Claudia HawkinsDepartment of Medicine, Robert J Havey Institute of Global Health, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, US.ORCID 0000-0001-7228-6317
Northwestern University · USMuhimbili University of Health and Allied Sciences · TZManagement and Development for Health · TZ

Funding

Building capacity for patient-centered outcomes research to improve the quality and impact of HIV care in TanzaniaD43TW010946 · FIC · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HAWKINS, CLAUDIA A, HIRSCHHORN, LISA · 2019 to 2023
$1.7M
FIC NIH HHS D43 TW010946
6 · The paper itself

Abstract

Background: Ageing adults living with HIV (ALHIV) have increased risk of cardiovascular diseases as a result of HIV-infection-related chronic immune activation and inflammatory responses. Cardiovascular health index (CVHI) is a valid and relatively simple index for assessing the cardiovascular health (CVH) of the general population. Use of this index among ALHIV in Sub Saharan Africa, a resource-restricted setting where it could be mostly beneficial, remains limited. Understanding of the distribution and associated factors may inform the design of optimal interventions to improve CVH of ALHIV. Objective: We aimed to assess the distribution and factors associated with CVHI scores among ALHIV in an urban setting in Tanzania. Methods: A cross-sectional study was conducted among ALHIV on antiretroviral therapy at six HIV clinics in Dar-es-Salaam, Tanzania. We summed the score of each of the seven CVHI metric to obtain the overall CVHI score and assessed the distribution of the score by sex. We then categorized the overall score into ideal (5-7), intermediate (3-4) and poor (<3) CVH categories and performed ordinal regression to identify CVHI score associated factors. Results: In all, 629 ALHIV [mean age of 43.5(SD ± 11.2) years] were enrolled. Most had ideal levels of blood glucose (96.2%) and smoking status (83.4%) while less than half had ideal BMI (48.1%), blood pressure (BP) (43.9%) and dietary intake (7.8%). Less than half (47.6%) showed ideal CVH, while less than 1% had all seven metrics at ideal level. Older age (0.96(95%CI:0.95-0.97), p-value < 0.001), being retired/unemployed (0.59(95%CI:0.43-0.81), p-value < 0.01), being employed (0.76(95%CI:0.62-0.94), p-value = 0.01) alcohol use (0.41(95%CI:0.21-0.80), p-value = 0.01) and presence of non-communicable disease comorbidities (0.68(95%CI:0.48-0.97), p-value = 0.04) had significant lower odds of ideal CVH. Conclusion: Based on our findings, interventions to improve CVH of ALHIV should target BP management, health education on diet for BMI control and reduction in alcohol consumption, particularly among ageing ALHIV with comorbidities.

Indexed as

Cardiovascular DiseasesHealth StatusAdultBlood PressureCross-Sectional StudiesHumansRisk FactorsTanzaniacardiovascular diseasescardiovascular health indexHIVideal cardiovascular healthTanzania

Identifiers

PMID36382155
PMCPMC9562968
OpenAlexW4304688848

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.