Evidence map›Paper›PMID 36382045›Full record

ArticleJournal of advanced veterinary and animal research2022

Identification of lipid regulatory genes modulated by polyherbal formulation in chicken liver tissues using transcriptome analysis.

Saravanakumar Marimuthu, Subramaniyam Suresh, Prashanth D'Souza

Open access · goldAbstract read
In one paragraph

Article in Journal of advanced veterinary and animal research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. The anti-obesity properties ofJournal of advanced veterinary and animal research · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Saravanakumar MarimuthuR & D Centre, Natural Remedies Private Limited, Bengaluru, India.
Subramaniyam SureshR & D Centre, Natural Remedies Private Limited, Bengaluru, India.
Prashanth D'SouzaR & D Centre, Natural Remedies Private Limited, Bengaluru, India.
Natural Remedies (India) · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To elucidate the cellular mechanisms of polyherbal formulation [Kolin Plus Materials and Methods: The gene expression patterns were studied for four groups [normal diet: normal, choline chloride deficient (CCD), KP (400 gm/ton), and CCL (400 gm/ton)] using Agilent microarray on day 42. The hierarchical cluster analysis was carried out on 12,614 differentially expressed genes (DEGs) with a similar expression. Results: Out of 12,614 significant DEGs, 1,926, 448, and 1,330 genes were expressed at higher rates, and 413, 482, and 1,364 were expressed at lower rates than CCD (CCD Conclusions: These findings reveal that the supplementation of KP prevents fatty liver-associated problems in broiler chickens by modulating the expression of the above-mentioned genes that are responsible for the oxidation of fatty acids and lipogenesis in the liver.

Indexed as

CCLKPlipid metabolismlipogenesisoxidationtranscriptome

Identifiers

PMID36382045
PMCPMC9597915
OpenAlexW4309244937

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.