Evidence map›Paper›PMID 36381994›Full record

SynthesisInternational journal of chronic obstructive pulmonary disease2022

Effects of High-Frequency Chest Wall Oscillation on Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Hsiao-Ping Huang, Kee-Hsin Chen, Chen-Liang Tsai, Wen-Pei Chang, Sherry Yueh-Hsia Chiu, Shin-Rou Lin, Yu-Huei Lin

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in International journal of chronic obstructive pulmonary disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Article
  3. Physiology-Guided Selection of Hardware-Assisted Airway Clearance Techniques during Acute Exacerbations of Non-Cystic Fibrosis Bronchiectasis.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Severe respiratory syncytial virus disease.Journal of intensive medicine · 2024
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Hsiao-Ping HuangNursing Department, Center for Nursing and Healthcare Research in Clinical Practice Application, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.
Kee-Hsin ChenPost-Baccalaureate Program in Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan.
Chen-Liang TsaiDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.ORCID 0000-0001-9783-5423
Wen-Pei ChangDepartment of Nursing, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.
Sherry Yueh-Hsia ChiuDepartment of Health Care Management, College of Management, Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan.
Shin-Rou LinDepartment of Health Care Management, College of Management, Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan.
Yu-Huei LinPost-Baccalaureate Program in Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan.ORCID 0000-0002-8382-9820
Chang Gung University · TWTaipei Medical University · TWTaipei Medical University Hospital · TWTaipei Medical University-Shuang Ho Hospital · TWTri-Service General Hospital · TWWan Fang Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study aimed to evaluate the efficacy of high-frequency chest wall oscillation for sputum expectoration and hospital length of stay in patients with acute exacerbations of chronic obstructive pulmonary disease. The improvements in pulmonary function and oxygenation were also investigated. Patients and Methods: This systematic review and meta-analysis followed the Preferred Reporting Items for Systematic Review and Meta-analyses (PRISMA) guidelines. Automated literature database searches were conducted from the earliest records to March 31, 2022. The methodological quality of the included studies was assessed using the Cochrane Risk of Bias tool (RoB 2.0), and meta-analysis software (RevMan 5.4) was used to analyze the data. Results: From 5439 identified articles, 13 studies (with 756 patients) were included in this meta-analysis. Compared to other airway clearance techniques, HFCWO significantly increased expectorated sputum volume by 6.18 mL (95% CI: 1.71 to 10.64; I Conclusion: AECOPD patients may benefit from HFCWO therapy. HFCWO enables AECOPD patients to excrete more sputum and shorten their hospital stays. However, due to heterogeneity among the included research, these results should be interpreted with caution.

Indexed as

Chest Wall OscillationPulmonary Disease, Chronic ObstructiveHumansLungRandomized Controlled Trials as TopicSputumacute exacerbation of chronic obstructive pulmonary diseaseAECOPDHFCWOhigh-frequency chest wall oscillationlength of hospital staysputum expectoration

Identifiers

PMID36381994
PMCPMC9661913
OpenAlexW4308728275

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.