Evidence map›Paper›PMID 36381958›Full record

ArticleImmune network2022

Efficient Anti-Tumor Immunotherapy Using Tumor Epitope-Coated Biodegradable Nanoparticles Combined With Polyinosinic-Polycytidylic Acid and an Anti-PD1 Monoclonal Antibody.

Sang-Hyun Kim, Ji-Hyun Park, Sun-Jae Lee, Hee-Sung Lee, Jae-Kyung Jung, Young-Ran Lee, Hyun-Il Cho, Jeong-Ki Kim, Kyungjae Kim, Chan-Su Park and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Immune network, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Sang-Hyun KimDepartment of Pharmaceutics, College of Pharmacy, Chungbuk National University, Cheongju 28644, Korea.ORCID https://orcid.org/0000-0002-7360-0491
Ji-Hyun ParkDepartment of Pharmaceutics, College of Pharmacy, Chungbuk National University, Cheongju 28644, Korea.ORCID https://orcid.org/0000-0002-2286-2029
Sun-Jae LeeDepartment of Pharmaceutics, College of Pharmacy, Chungbuk National University, Cheongju 28644, Korea.ORCID https://orcid.org/0000-0001-9135-2738
Hee-Sung LeeDepartment of Pharmaceutics, College of Pharmacy, Chungbuk National University, Cheongju 28644, Korea.ORCID https://orcid.org/0000-0001-6166-5346
Jae-Kyung JungDepartment of Pharmaceutics, College of Pharmacy, Chungbuk National University, Cheongju 28644, Korea.ORCID https://orcid.org/0000-0002-0490-9663
Young-Ran LeeCenter for Convergence Bioceramic Materials, Korea Institute of Ceramic Engineering and Technology, Cheongju 28160, Korea.ORCID https://orcid.org/0000-0001-8696-5513
Hyun-Il ChoResearch and Development Division, ViGenCell Inc., Seoul 06591, Korea.ORCID https://orcid.org/0000-0002-6520-3066
Jeong-Ki KimDepartment of Pharmacy, Korea University College of Pharmacy, Sejong 30019, Korea.ORCID https://orcid.org/0000-0003-1520-1377
Kyungjae KimDepartment of Pharmacy, College of Pharmacy, Sahmyook University, Seoul 01795, Korea.ORCID https://orcid.org/0000-0002-0943-9306
Chan-Su ParkDepartment of Pharmaceutics, College of Pharmacy, Chungbuk National University, Cheongju 28644, Korea.ORCID https://orcid.org/0000-0003-4968-8304
Chong-Kil LeeDepartment of Pharmaceutics, College of Pharmacy, Chungbuk National University, Cheongju 28644, Korea.ORCID https://orcid.org/0000-0001-9070-341X
Chungbuk National University · KRKorea Institute of Ceramic Engineering and Technology · KRKorea University · KRNovaCell Technology (South Korea) · KRSahmyook University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccination with tumor peptide epitopes associated with MHC class I molecules is an attractive approach directed at inducing tumor-specific CTLs. However, challenges remain in improving the therapeutic efficacy of peptide epitope vaccines, including the low immunogenicity of peptide epitopes and insufficient stimulation of innate immune components

Indexed as

Anti-PD1 monoclonal antibodyCytotoxic T lymphocytesImmunotherapyPolyinosinic-polycytidylic acidTumor epitope nanoparticlesTumor peptide epitopes

Identifiers

PMID36381958
PMCPMC9634146
OpenAlexW4309245121

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.