Evidence map›Paper›PMID 36381851›Full record

ReviewCureus2022

Association of Gut Microbial Dysbiosis and Hypertension: A Systematic Review.

Shaili S Naik, Shivana Ramphall, Swarnima Rijal, Vishakh Prakash, Heba Ekladios, Jiya Mulayamkuzhiyil Saju, Naishal Mandal, Nang I Kham, Rabia Shahid, Sathish Venugopal

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. [Correlation between trimethylamine-N-oxide and cardiovascular metabolic markers].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Potential protective effects ofFrontiers in pharmacology · 2026
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Impact of aFoods (Basel, Switzerland) · 2025
    Article
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  16. Review
  17. Review
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  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Shaili S NaikInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Shivana RamphallInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Swarnima RijalInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Vishakh PrakashInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Heba EkladiosDepartment of Psychiatry, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Jiya Mulayamkuzhiyil SajuInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Naishal MandalInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Nang I KhamInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Rabia ShahidInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Sathish VenugopalInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Sardar Vallabhbhai National Institute of Technology Surat · INCalifornia Institute of Behavioral Neurosciences and Psychology (United States) · USGovernment College Kodanchery · INGovernment Medical College · INGovernment Medical College and Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertension (HTN) is one of the most prevalent and dangerous cardiovascular diseases worldwide. Recently, its direct or indirect association with gut dysbiosis has been an interest of study for many. It also includes the metabolomic and functional gene changes in hypertensives compared with healthy individuals. This systematic review aims to study quantitative and qualitative interactions between the two and re-defining the heart-gut axis. We have strictly followed the

Indexed as

gut dysbiosisgut microbiomehigh blood pressurehypertensionintestinal symbiosis

Identifiers

PMID36381851
PMCPMC9642844
OpenAlexW4301431091

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.