Evidence map›Paper›PMID 36381814›Full record

ArticleCureus2022

Resistant Hypertension in Patients With Type-2 Diabetes Mellitus: A Single-Center, Cross-Sectional Study.

Aqeel S Binaqeel, Hossein A Filimban, Abdullah A Fallatah, Salman W Bafageeh, Sara H Al Khansa, Bader K Al Aslab, Rayan S Alzahrani, Leyan R Bakedo, Ahmed Abuosa, Ibrahim Jelaidan

Open access · diamondAbstract read
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 76% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 0 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Aqeel S BinaqeelCollege of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.
Hossein A FilimbanCollege of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.
Abdullah A FallatahCollege of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.
Salman W BafageehCollege of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.
Sara H Al KhansaPharmaceutical Care Services, King Abdulaziz Cardiac Center, National Guard Health Affairs, Jeddah, SAU.
Bader K Al AslabCollege of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.
Rayan S AlzahraniCollege of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.
Leyan R BakedoMedicine and Surgery, King Abdulaziz University, Jeddah, SAU.
Ahmed AbuosaCardiology, National Training Institute, Cairo, EGY.
Ibrahim JelaidanCardiology, King Abdulaziz Cardiac Center, National Guard Health Affairs, Jeddah, SAU.
Cairo University · EGKing Abdulaziz University · SANational Guard Health Affairs · SAKing Saud bin Abdulaziz University for Health Sciences · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background The prevalence of resistant hypertension in Saudi patients with type-2 diabetes mellitus (T2DM) has not been previously estimated. Therefore, our objective was to assess the prevalence and characteristics of resistant hypertensive patients with T2DM at King Abdulaziz Medical City, Jeddah, Saudi Arabia. Methods This cross-sectional study included patients with hypertension and T2DM who presented to our center in 2018. We examined 1960 patients with T2DM during the study period; 809 were hypertensives. We compared T2DM patients with controlled hypertension versus resistant hypertension. Results The prevalence of resistant hypertension in patients with T2DM was 137/809 (16.93%). The mean age was 66.38±10.80 years, and females presented 56% of the study population (n= 451). Obstructive sleep apnea (OSA; OR: 2.60 [1.15- 5.87]; P=0.02) and ischemic heart disease (IHD; OR: 3.01 [2.04- 4.45]; P˂0.001) were significantly associated with resistant hypertension. The most common medications used with resistant hypertension were calcium channel blockers (CCBs; 89.05%), β-blockers (76.64%), and angiotensin-2 receptor blockers (ARBs; 62.77%). Conclusions Resistant hypertension in patients with T2DM is common in Saudi Arabia. Resistant hypertension could be associated with OSA and IHD. Further studies are required to evaluate the temporal relationship between resistant hypertension and risk factors.

Indexed as

antihypertensiveshypertensionischemic heart diseaseprevalenceresistant hypertensiontype-2 diabetes mellitus

Identifiers

PMID36381814
PMCPMC9651209
OpenAlexW4304776358

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.