Evidence map›Paper›PMID 36381802›Full record

ArticleCureus2022

Mechanical Alignment in Total Knee Arthroplasty for Varus Knee Osteoarthritis Leads to Significant Tibial Bone Loss.

Ashim Mannan, Ahmed Y Saber, Ben Waterson, Andrew Roberton, Andrew Toms

Open access · diamondAbstract read
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Challenging the neutral axis: 15-year results of under-corrected varus in total knee arthroplasty.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ashim MannanExeter Knee Reconstruction Unit - Princess Elizabeth Orthopaedic Centre, Royal Devon and Exeter NHS Foundation Trust, Exeter, GBR.
Ahmed Y SaberExeter Knee Reconstruction Unit - Princess Elizabeth Orthopaedic Centre, Royal Devon and Exeter NHS Foundation Trust, Exeter, GBR.
Ben WatersonExeter Knee Reconstruction Unit - Princess Elizabeth Orthopaedic Centre, Royal Devon and Exeter NHS Foundation Trust, Exeter, GBR.
Andrew RobertonExeter Knee Reconstruction Unit - Princess Elizabeth Orthopaedic Centre, Royal Devon and Exeter NHS Foundation Trust, Exeter, GBR.
Andrew TomsExeter Knee Reconstruction Unit - Princess Elizabeth Orthopaedic Centre, Royal Devon and Exeter NHS Foundation Trust, Exeter, GBR.
Princess Elizabeth Orthopaedic Centre · GBRoyal Devon & Exeter NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Obtaining a neutral postoperative alignment is said to be a guiding principle for performing a successful total knee arthroplasty (TKA). There are many different alignment philosophies and surgical techniques to attain the goal of proper alignment. This study aimed to radiologically measure the difference in the amount of tibial bony resection required to perform a mechanical alignment versus an anatomic alignment TKA. Methods Two observers retrospectively reviewed the long leg radiographs of 100 patients (61 females and 39 males) listed for TKA between 2015 and 2018, measuring the amount of tibial bony resection required to achieve mechanical or anatomic alignment TKA. Results These radiographs' overall lower limb mechanical axis ranged between 16° varus and 17.6° valgus (mean 4.4° varus, standard deviation (SD) 6.64). By referencing 4 mm from the worn side, the mean resection needed from the normal side of the tibial plateau is 7.6 mm in the mechanical alignment measurement and 5.2 mm in the anatomical alignment measurement (p<0.0001). Therefore, 17% of mechanical alignment cuts require a tibial cut of more than 10 mm (mean 12.382 mm). No anatomical alignment measurements exceed 10 mm. When a virtual tibial cut >10 mm is required, the medial proximal tibial angle (MPTA) is a stronger predictor of deformity than the mechanical axis. Conclusion This radiological study shows that an anatomical alignment tibial cut is more bone conserving on the tibia than a mechanical alignment tibial cut and may lead to less asymmetry of the bony cuts and greater bony preservation, but clinical correlation is needed.

Indexed as

anatomical alignmentknee arthroplastymechanical alignmenttibial cuttotal knee arthroplasty techniquevarus knee

Identifiers

PMID36381802
PMCPMC9643100
OpenAlexW4303945802

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.