Evidence map›Paper›PMID 36381788›Full record

ReviewCureus2022

The Comparison of Therapeutic With Prophylactic Anticoagulation on Mortality, Risk of Bleeding, and Thromboembolism in Hospitalized Patients With COVID-19: A Systematic Review.

Nang I Kham, Rabia Shahid, Shaili S Naik, Shivana Ramphall, Swarnima Rijal, Vishakh Prakash, Heba Ekladios, Jiya Mulayamkuzhiyil Saju, Naishal Mandal, Prachi Balani

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 4 countries.

Nang I KhamInternal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Rabia ShahidInternal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Shaili S NaikInternal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Shivana RamphallInternal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Swarnima RijalInternal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Vishakh PrakashInternal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Heba EkladiosPsychiatry, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Jiya Mulayamkuzhiyil SajuInternal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Naishal MandalInternal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Prachi BalaniInternal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Government Medical College · INAmerican University of Antigua · AGCalifornia Institute of Behavioral Neurosciences and Psychology (United States) · USGovernment College Kodanchery · INGovernment Medical College · INSaint Vincent Hospital · USUniversity Of Medicine 1 Yangon · MM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thromboembolism is one of the most severe manifestations of coronavirus disease 2019 (COVID-19). Thrombotic complications have been reported even with the administration of thromboprophylaxis. This has led many experts to have variable opinions on the most effective prophylactic strategy and to anticipate the discovery of the ideal dosing of anticoagulation to reduce thromboembolic events and related mortality. We performed a systematic review to evaluate whether therapeutic-dose anticoagulation is superior to prophylactic-dose anticoagulation by comparing mortality rates, bleeding risks, and rates of thromboembolism. We adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines to create our systematic review. Twenty-two records were collected from PubMed, PubMed Central (PMC), and Medical Literature Analysis and Retrieval System Online (MEDLINE), after which they undertook quality appraisals. A total of 124 studies were analyzed in six systematic reviews and meta-analyses, one pooled analysis, two multicenter retrospective cohort studies, one observational study, one retrospective chart review, one evidence-based protocol, and four narrative reviews.

Indexed as

arteriovenous thromboembolism in sars-cov-2-infected patientscoronavirus disease 2019 (covid-19)critical hemorrhagic complicationsprophylactic anticoagulationrisk of covid-19 mortalitytherapeutic anticoagulation

Identifiers

PMID36381788
PMCPMC9635931
OpenAlexW4301585135

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.