Evidence map›Paper›PMID 36381730›Full record

ArticleCureus2022

Antineutrophil Cytoplasmic Antibody (ANCA)-Associated Renal Vasculitis Following COVID-19 Vaccination: A Case Report and Literature Review.

Khalid Uddin, Khalid H Mohamed, Adesola A Agboola, Warda A Naqvi, Helai Hussaini, Alaa S Mohamed, Muhammad Haseeb, Hira Nasir

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 5 countries.

Khalid UddinNeurology, Henry Ford Health System, Detroit, USA.
Khalid H MohamedNeurology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, GBR.
Adesola A AgboolaPathology and Laboratory Medicine, Dele Hospitals, Lagos, NGA.
Warda A NaqviInfectious Diseases, Shifa International Hospital, Islamabad, PAK.
Helai HussainiInternal Medicine, Toronto General Hospital, Toronto, CAN.
Alaa S MohamedNeurology, Augusta University, Augusta, USA.
Muhammad HaseebInternal Medicine, Jinnah Hospital Lahore, Lahore, PAK.
Hira NasirInternal Medicine, Mayo Hospital, Lahore, PAK.
Mayo Hospital · PKAugusta University Health · USLagos University Teaching Hospital · NGToronto General Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is an immune-mediated disorder of small and medium-sized vessels, characterized by the production of autoantibodies that target the neutrophilic antigens leading to mononuclear cell infiltration and destruction of blood vessels in lungs, skin, and kidneys. Although rare, the coronavirus disease 2019 (COVID-19) vaccine may trigger autoimmune vasculitis. We report a rare case of ANCA-associated renal vasculitis following COVID-19 vaccination in a 59-year-old male who presented with flu-like symptoms and deranged renal function tests. He received his second dose of the Pfizer COVID-19 vaccine 17 days ago. His clinical picture, serological testing, and radiological imaging were concerned with glomerular disease. His serum was positive for ANCAs, and the renal biopsy specimen revealed pauci-immune glomerulonephritis. He was diagnosed with AAV-associated renal vasculitis following COVID-19 vaccination because no other etiology was identified. His clinical improvement after starting rituximab and steroids reinforced the diagnosis.

Indexed as

anca-associated vasculitisantineutrophil cytoplasmic antibodycovid-19covid-19 vaccinecovid-19 vaccine complicationpauci-immune anti-neutrophil cytoplasmic antibody (anca)-associated vasculitis (aav)pauci-immune glomerulonephritis (gn)renal vasculitisvasculitis

Identifiers

PMID36381730
PMCPMC9650918
OpenAlexW4304787565

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.