Evidence map›Paper›PMID 36381691›Full record

ReviewCureus2022

Fertility and Pregnancy Outcomes in Patients With Adenomyosis: Is Adenomyosis Synonymous With Infertility?

Maria Jose Calero, Maria Resah B Villanueva, Narges Joshaghani, Nicole Villa, Omar Badla, Raman Goit, Samia E Saddik, Sarah N Dawood, Ahmad M Rabih, Aishwarya Raman and 3 more

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Maria Jose CaleroObstetrics and Gynecology, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Maria Resah B VillanuevaResearch, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Narges JoshaghaniPsychiatry and Behavioral Sciences, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Nicole VillaInternal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Omar BadlaGeneral Surgery, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Raman GoitInternal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Samia E SaddikInternal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Sarah N DawoodPediatrics, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Ahmad M RabihInternal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Aishwarya RamanInternal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Manish UpretyInternal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Ahmad MohammedInternal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Lubna MohammedInternal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
California Institute of Behavioral Neurosciences and Psychology (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adenomyosis is a disease related to the presence of endometrial glands and stromal cells within the uterine myometrium that used to be linked to females that are more than 40 years old and multiparous. Nowadays, females are delaying their pregnancies to their third or fourth decade, and as diagnostic approaches evolve, the disease has become a common problem for females who desire pregnancy. The aim of this study is to identify the physio-pathological factors by which adenomyosis causes infertility and pregnancy complications, as well as the possible results from infertility treatments and the most common pregnancy complications that females with adenomyosis face. A systematic review based on a systematic search from PubMed, Cochrane, and ScienceDirect databases from the past five years was done. Papers with free full text available were subject to the removal of duplicates, screening for relevant titles and abstracts, and a quality assessment to identify the risk of bias (RoB). A total of 10 papers were selected for this study; they include systematic reviews and meta-analyses, cohorts, literature review, and a case-control study. After the review of the data, we conclude that infertility may be due to several factors that impair adequate sperm mobility through the uterus and an impaired implantation of a product. After some fertility treatments were performed, females with adenomyosis had a lower rate of clinical pregnancy. The pregnancy complications such as preterm delivery and hypertension problems related to pregnancy had an increased risk for females with adenomyosis, while for others such as intrauterine fetal death and gestational diabetes, the information is still controversial. The main limitation of this study was the lack of information of physio-pathological-related information probably due to only including data from the past five years.

Indexed as

adenomyosisfertilityinfertilityobstetrical outcomespregnancypregnancy outcomes

Identifiers

PMID36381691
PMCPMC9650954
OpenAlexW4306247194

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.