Evidence map›Paper›PMID 36381673›Full record

ArticleContemporary oncology (Poznan, Poland)2022

Outcome of docetaxel in treatment of metastatic hormone-sensitive prostate cancer and correlation with hemoglobin, albumin, lymphocyte and platelets score.

Heba F Taha, Dalia Hamouda Elsayed, Reham Salem, Doaa Mandour, Mohammed Bayomy, Hayam Rashed, Mostafa Kamel, Mohamed Elderey, Ola M Elfarargy

Open access · goldAbstract read
In one paragraph

Article in Contemporary oncology (Poznan, Poland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Heba F TahaMedical Oncology Department, Zagazig University, Zagazig, Egypt.
Dalia Hamouda ElsayedMedical Oncology Department, Zagazig University, Zagazig, Egypt.
Reham SalemClinical Oncology and nuclear medicine department, Zagazig University, Zagazig, Egypt.
Doaa MandourClinical Oncology and nuclear medicine department, Zagazig University, Zagazig, Egypt.
Mohammed BayomyClinical Oncology and nuclear medicine department, Zagazig University, Zagazig, Egypt.
Hayam RashedPathology Department, Zagazig University, Zagazig, Egypt.
Mostafa KamelUrology Department, Zagazig University, Zagazig, Egypt.
Mohamed EldereyUrology Department, Zagazig University, Zagazig, Egypt.
Ola M ElfarargyMedical Oncology Department, Zagazig University, Zagazig, Egypt.
Zagazig University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: We aimed to evaluate the outcome of treatment with docetaxel plus androgen deprivation therapy (ADT) in newly diagnosed patients with metastatic high tumor burden hormone-sensitive prostate cancer (mHSPC) and correlated the outcome with hemoglobin, albumin, lymphocyte and platelets (HALP) score. Material and methods: Six cycles of docetaxel plus ADT were given to 50 patients with high burden mHSPC. Baseline HALP score was calculated and disease outcome was tabulated; moreover, the prognostic impact of the HALP score in response to treatment and survival was calculated. Results: We found a significant association between high HALP score and response to treatment where a higher rate of complete response occurred in patients with a high HALP score than in patients with a low HALP score (53.8% vs. 5.4% respectively, Conclusions: Our results confirmed the benefits of treatment with docetaxel plus ADT in high-burden mHSPC with accepted tolerance. HALP score was found to be an independent predictive factor for benefit from therapy; we can apply it as an easy way to stratify patients for appropriate selection of treatment for better tolerance and outcome.

Indexed as

docetaxelHALP scorehigh burdenhormone-sensitivemetastatic prostatic cancer

Identifiers

PMID36381673
PMCPMC9641632
OpenAlexW4309246057

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.