Evidence map›Paper›PMID 36381650›Full record

ArticleNeuro-oncology practice2022

Imaging in patients with glioblastoma: A national cohort study.

Maureen Dumba, Anna Fry, Jon Shelton, Thomas C Booth, Brynmor Jones, Haris Shuaib, Matt Williams

Abstract read
In one paragraph

Article in Neuro-oncology practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Observational
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Maureen DumbaDepartment of Neuroradiology, Imperial College Healthcare NHS Trust, London, UK.ORCID https://orcid.org/0000-0003-1745-6074
Anna FryCancer Research UK, London, UK.
Jon SheltonCancer Research UK, London, UK.
Thomas C BoothDepartment of Neuroradiology, King's College Hospital NHS Foundation Trust, London, UK.
Brynmor JonesDepartment of Neuroradiology, Imperial College Healthcare NHS Trust, London, UK.
Haris ShuaibDepartment of Medical Physics, Guy's & St. Thomas' NHS Foundation Trust, London, UK.
Matt WilliamsDepartment of Radiotherapy, Imperial College Healthcare NHS Trust, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Glioblastoma is the most common malignant brain tumor in adults and has a poor prognosis. This cohort of patients is diverse and imaging is vital to formulate treatment plans. Despite this, there is relatively little data on patterns of use of imaging and imaging workload in routine practice. Methods: We examined imaging patterns for all patients aged 15-99 years resident in England who were diagnosed with a glioblastoma between 1st January 2013 and 31st December 2014. Patients without imaging and death-certificate-only registrations were excluded. Results: The analytical cohort contained 4,307 patients. There was no significant variation in pre- or postdiagnostic imaging practice by sex or deprivation quintile. Postdiagnostic imaging practice was varied. In the group of patients who were treated most aggressively (surgical debulking and chemoradiation) and were MRI compatible, only 51% had a postoperative MRI within 72 hours of surgery. In patients undergoing surgery who subsequently received radiotherapy, only 61% had a postsurgery and preradiotherapy MRI. Conclusions: Prediagnostic imaging practice is uniform. Postdiagnostic imaging practice was variable. With increasing evidence and clearer recommendations regarding debulking surgery and planning radiotherapy imaging, the reason for this is unclear and will form the basis of further work.

Indexed as

glioblastomaimagingoutcomesradiotherapysurgery

Identifiers

PMID36381650
PMCPMC9665056

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.